{"id":132,"date":"2016-04-13T11:07:40","date_gmt":"2016-04-13T02:07:40","guid":{"rendered":"http:\/\/h-crisis.niph.go.jp\/bt\/?page_id=132"},"modified":"2020-01-27T18:05:00","modified_gmt":"2020-01-27T09:05:00","slug":"14summary","status":"publish","type":"page","link":"https:\/\/h-crisis.niph.go.jp\/bt\/disease\/14summary\/","title":{"rendered":"\uff11\uff14\uff0e\u591a\u5264\u8010\u6027\u7d50\u6838\u83cc &#8211; Multiple Drug Resistance tuberculosis"},"content":{"rendered":"<h2>\u30b5\u30de\u30ea\u30fc<\/h2>\n<ol>\n<li style=\"list-style-type: none\">\n<ol>\n<li>\u00a0\u75c5\u539f\u4f53\u306e\u7279\u5fb4\n<ul>\n<li>\u539f\u56e0\u75c5\u539f\u4f53\uff1a\u7d50\u6838\u83cc\uff08Mycobacterium tuberculosis\uff09<\/li>\n<li>\u6297\u9178\u83cc\u5c5e\u3001\u7d50\u6838\u83cc\u7fa4\u3000\u504f\u6027\u597d\u6c17\u6027\u83cc\u3001\u30b0\u30e9\u30e0\u967d\u6027\u687f\u83cc<\/li>\n<li>\u6297\u9178\u83cc\u67d3\u8272\u3067\u8d64\u6a59\u8272\u306e\u687f\u83cc\u3001\u9178\u30fb\u30a2\u30eb\u30ab\u30ea\u306b\u62b5\u6297\u6027<\/li>\n<\/ul>\n<\/li>\n<li>\u5206\u985e\u3068\u6f5c\u4f0f\u671f\u9593\n<ul>\n<li>\u611f\u67d3\u5f8c\u306e\u767a\u75c5\u69d8\u5f0f\u304b\u3089\u3001\u4e00\u6b21\u7d50\u6838\u3001\u4e8c\u6b21\u7d50\u6838\u3068\u306b\u5206\u985e\u3055\u308c\u308b\u3002\u307e\u305f\u3001\u7f79\u60a3\u81d3\u5668\u306b\u3088\u308a\u80ba\u7d50\u6838\u3001\u8178\u7d50\u6838\u3001\u7d50\u6838\u6027\u30ea\u30f3\u30d1\u7bc0\u708e\u3001\u7c9f\u7c92\u7d50\u6838\u7b49\u306b\u5206\u985e\u3055\u308c\u308b\u3002<\/li>\n<\/ul>\n<\/li>\n<li>\u611f\u67d3\u7d4c\u8def\n<ul>\n<li>\u7a7a\u6c17\u611f\u67d3\uff08\u98db\u6cab\u6838\u3068\u306a\u3063\u305f\u7d50\u6838\u83cc\u3092\u5438\u5165\u3059\u308b\u3053\u3068\u306b\u3088\u308a\u611f\u67d3\u304c\u6210\u7acb\u3059\u308b\uff09\u3042\u308b\u3044\u306f\u98db\u6cab\u611f\u67d3<\/li>\n<\/ul>\n<\/li>\n<li>\u81e8\u5e8a\u75c7\u72b6\n<ul>\n<li>\u80ba\u7d50\u6838\n<ul>\n<li>\u54b3\u55fd\u3001\u5580\u75f0\uff08\u3068\u304d\u306b\u8840\u75f0\uff09\u3001\u767a\u71b1\uff08\u901a\u5e38\u5fae\u71b1\uff09\u3001\u80f8\u75db\u3001\u98df\u6b32\u4f4e\u4e0b\u3001\u4f53\u91cd\u6e1b\u5c11\u3001\u76d7\u6c57\u3001\u547c\u5438\u56f0\u96e3\u306a\u3069<\/li>\n<\/ul>\n<\/li>\n<li>\u7d50\u6838\u6027\u30ea\u30f3\u30d1\u7bc0\u708e\n<ul>\n<li>\u30ea\u30f3\u30d1\u7bc0\u816b\u8139\u3001\u767a\u71b1\u306a\u3069<\/li>\n<\/ul>\n<\/li>\n<li>\u7c9f\u7c92\u7d50\u6838\n<ul>\n<li>\u767a\u71b1\uff08\u4e00\u822c\u7684\u306b\u9ad8\u71b1\uff09\u3001\u5026\u6020\u611f\u3001\u98df\u6b32\u4f4e\u4e0b\u3001\u547c\u5438\u56f0\u96e3\u3001\u610f\u8b58\u969c\u5bb3\u306a\u3069<\/li>\n<\/ul>\n<\/li>\n<li>\u7d50\u6838\u6027\u9ac4\u819c\u708e\n<ul>\n<li>\u767a\u71b1\u3001\u982d\u75db\u3001\u60aa\u5fc3\u3001\u5614\u5410\u3001\u610f\u8b58\u969c\u5bb3\u306a\u3069<\/li>\n<\/ul>\n<\/li>\n<li>\u8178\u7d50\u6838\n<ul>\n<li>\u767a\u71b1\u3001\u8840\u4fbf\u30fb\u4fbf\u901a\u7570\u5e38\u3001\u8179\u75db\u3001\u8179\u90e8\u816b\u7624\u306a\u3069<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<li>\u691c\u4f53\u306e\u7a2e\u985e\u304a\u3088\u3073\u63a1\u53d6\u6cd5\n<ul>\n<li>\u80ba\u7d50\u6838\n<ul>\n<li>\u5580\u75f0\u3001\u80c3\u6db2\u3001\u6c17\u7ba1\u652f\u6d17\u6d44\u6db2\u306a\u3069<\/li>\n<li>\u305d\u306e\u4ed6\u3001\u7f79\u60a3\u81d3\u5668\u306b\u3088\u3063\u3066\u8840\u6db2\u3001\u9ac4\u6db2\u3001\u80f8\u6c34\u3001\u8179\u6c34\u3001\u5c3f\u3001\u4fbf\u3001\u9aa8\u9ac4\u3001\u751f\u691c\u7d44\u7e54\u306a\u3069..<\/li>\n<li>\u8d77\u5e8a\u6642\u306b\u9023\u7d9a3\u65e5\u9593\u63a1\u75f0\u304c\u671b\u307e\u3057\u3044<\/li>\n<li>\u81ea\u767a\u75f0\u304c\u5f97\u3089\u308c\u306a\u3044\u6642\u306f\u30013\u301c5%\u9ad8\u5f35\u98df\u5869\u6c34\u3092\u5438\u5165\u3055\u305b\u8a98\u767a\u3059\u308b\u304b\u3001\u8d77\u5e8a\u5f8c\u7a7a\u8179\u6642\u306b\u80c3\u6db2\u3092\u63a1\u53d6\u3059\u308b\u3002<\/li>\n<li>\u968f\u6642\u75f0\u3067\u3042\u3063\u3066\u3082\u81bf\u6027\u3067\u3042\u308c\u3070\u8a3a\u65ad\u4fa1\u5024\u306f\u9ad8\u3044\u3002<\/li>\n<li>\u5341\u5206\u306a\u5580\u75f0\u304c\u5f97\u3089\u308c\u306a\u3044\u75c7\u4f8b\u3067\u306f\u6c17\u7ba1\u652f\u93e1\u691c\u67fb\u306b\u3088\u308b\u6c17\u7ba1\u652f\uff08\u80ba\u80de\uff09\u6d17\u6d44\u6db2\u306e\u63a1\u53d6\u3092\u8003\u616e\u3059\u308b\u3002<\/li>\n<\/ul>\n<\/li>\n<li>\u4f53\u8154\u6db2\uff08\u80f8\u6c34\u3001\u8179\u6c34\u306a\u3069\n<ul>\n<li>\u7121\u83cc\u7684\u306b\u63a1\u53d6\u3059\u308b\u3002<\/li>\n<li>\u8a3a\u65ad\u7387\u5411\u4e0a\u306e\u305f\u3081\u53ef\u80fd\u306a\u9650\u308a\u5927\u91cf\u306b\u63a1\u53d6\u3059\u308b\u3002<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<li>\u5fae\u751f\u7269\u5b66\u7684\u691c\u67fb\u6cd5\n<ul>\n<li>\u308f\u304c\u56fd\u3067\u306f\u4e00\u822c\u7684\u306b\u300c\u7d50\u6838\u83cc\u691c\u67fb\u6307\u91dd2007\u300d\u306b\u5f93\u3063\u3066\u7d50\u6838\u83cc\u691c\u67fb\u3092\u884c\u3046\u3002\n<ul>\n<li>\u5857\u62b9\u67d3\u8272\u00a0\u6297\u9178\u83cc\u67d3\u8272\uff08Ziehl-Neelsen\u67d3\u8272\uff09\uff1a\u8d64\u6a59\u8272\u306e\u687f\u83cc\n<ul>\n<li>\u6297\u9178\u83cc\u67d3\u8272\uff08Ziehl-Neelsen\u67d3\u8272\uff09\uff1a\u8d64\u6a59\u8272\u306e\u687f\u83cc<\/li>\n<li>\u86cd\u5149\u67d3\u8272\uff08\u30aa\u30fc\u30e9\u30df\u30f3\u67d3\u8272\uff09<\/li>\n<\/ul>\n<\/li>\n<li>\u57f9\u990a\n<ul>\n<li>\u5c0f\u5ddd\u57f9\u5730\u3001MGIT\u57f9\u5730(Mycobacteria Growth Indicator Tube)\uff08BACTEC MGIT 960\u30b7\u30b9\u30c6\u30e0\u3092\u542b\u3080\uff09\u3001KRD\u57f9\u5730\u3001BacteAlert 3D\u3001Middlebrook7H9\uff08\u6db2\u4f53\u57f9\u5730\uff09\u3001Middlebrook7H10\uff08\u5bd2\u5929\u57f9\u5730\uff09\u306a\u3069<\/li>\n<\/ul>\n<\/li>\n<li>\u7d50\u6838\u83cc\u691c\u51fa\u540c\u5b9a\u6cd5\uff08\u6838\u9178\u5897\u5e45\u6cd5\u3092\u542b\u3080\uff09\n<ul>\n<li>DDH\u30de\u30a4\u30b3\u30d0\u30af\u30c6\u30ea\u30a2\uff08\u6975\u6771\uff09<\/li>\n<li>\u30ad\u30e3\u30d4\u30ea\u30a2\u24c7TB<\/li>\n<li>PCR\u6cd5\uff08\u30b3\u30d0\u30b9\u30a2\u30f3\u30d7\u30ea\u30b3\u30a2TM\u30de\u30a4\u30b3\u30d0\u30af\u30c6\u30ea\u30a6\u30e0\u3001\u30b3\u30d0\u30b9TaqMan MTB\uff1aRoche\uff09<\/li>\n<li>RNA\u5897\u5e45\u6cd5\uff08MTD\u6cd5\uff1aGen-Probe\uff09<\/li>\n<li>TRC rapid M.TB\uff08\u6771\u30bd\u30fc\uff09\u306a\u3069<\/li>\n<\/ul>\n<\/li>\n<li>\u514d\u75ab\u5b66\u7684\u691c\u67fb\uff08\u7d50\u6838\u611f\u67d3\u306e\u6709\u7121\uff09\n<ul>\n<li>\u00a0\u7d50\u6838\u83ccIFN-\u03b3\u6e2c\u5b9a(IGRA)( T-SPOT TB, QFT-plus)<\/li>\n<\/ul>\n<\/li>\n<li>\u85ac\u5264\u611f\u53d7\u6027\u8a66\u9a13\uff08\u57f9\u990a\u6cd5\uff09\n<ul>\n<li>\u00a0\u85ac\u5264\u542b\u6709\u5c0f\u5ddd\u57f9\u5730\u3001\u30d6\u30ed\u30b9\u30df\u30c3\u30afMTB<\/li>\n<\/ul>\n<\/li>\n<li>\u85ac\u5264\u8010\u6027\u907a\u4f1d\u5b50\u691c\u51fa\n<ul>\n<li>\u30d5\u30a3\u30ce\u30b9LiPA\u30fbRifTB\uff08RFP\u8010\u6027\u83cc\u691c\u51fa\uff1a\u30cb\u30d7\u30ed\uff09<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<li>\u6297\u9178\u83cc\u83cc\u7a2e\u540c\u5b9a\u3001\u85ac\u5264\u611f\u53d7\u6027\u8a66\u9a13\u306b\u95a2\u3057\u3066\u306f\uff08\u8ca1\uff09\u7d50\u6838\u4e88\u9632\u4f1a\u7d50\u6838\u7814\u7a76\u6240\u6297\u9178\u83cc\u30ec\u30d5\u30a1\u30ec\u30f3\u30b9\u30bb\u30f3\u30bf\u30fc\u7d30\u83cc\u691c\u67fb\u79d1\u3067\u3082\u554f\u5408\u305b\u306b\u5fdc\u3058\u3066\u3044\u308b\u3002<\/li>\n<\/ul>\n<\/li>\n<li>\u611f\u67d3\u75c7\u306b\u304a\u3051\u308b\u53d6\u308a\u6271\u3044\n<ul>\n<li>\u5e73\u621019\u5e74\u306b\u7d50\u6838\u4e88\u9632\u6cd5\u304c\u6539\u6b63\u611f\u67d3\u75c7\u6cd5\u306b\u7d71\u5408\u3055\u308c\u308b\u5f62\u3068\u306a\u3063\u305f\u3002<\/li>\n<li>\u6539\u6b63\u611f\u67d3\u75c7\u6cd5\u3067\u306f\u7d50\u6838\u75c7\u3092\u4e8c\u985e\u611f\u67d3\u75c7\u3068\u3057\u3001\u75c5\u539f\u4f53\u3068\u3057\u3066\u591a\u5264\u8010\u6027\u7d50\u6838\u83cc\u3092\u4e09\u7a2e\u75c5\u539f\u4f53\uff08\u6240\u6301\u7b49\u306e\u5c4a\u51fa\uff09\u3001\u305d\u308c\u4ee5\u5916\u306e\u7d50\u6838\u83cc\u3092\u56db\u7a2e\u75c5\u539f\u4f53\u3068\u3057\u3066\u6271\u3063\u3066\u3044\u308b\u3002<\/li>\n<\/ul>\n<\/li>\n<li>\u60a3\u8005\u306e\u9694\u96e2\u3084\u6c5a\u67d3\u5668\u6750\u7b49\u306e\u7ba1\u7406\n<ul>\n<li>\u5857\u62b9\u967d\u6027\u60a3\u8005\u306a\u3069\u3001\u4ed6\u8005\u3078\u306e\u611f\u67d3\u6027\u304c\u9ad8\u3044\u8005\u306b\u3064\u3044\u3066\u306f\u6539\u6b63\u611f\u67d3\u75c7\u6cd5\u306b\u5f93\u3044\u5165\u9662\u52e7\u544a\u3092\u884c\u3046\u3002<\/li>\n<\/ul>\n<\/li>\n<li>\u6cbb\u7642\u306e\u8981\u70b9\n<ul>\n<li>\u57fa\u672c\u7684\u306b\u306f\u300c\u7d50\u6838\u533b\u7642\u306e\u57fa\u6e96\u300d\u306b\u6e96\u3058\u3066\u6cbb\u7642\u3092\u884c\u3046\n<ul>\n<li>\u521d\u56de\u6cbb\u7642\u6642\n<ul>\n<li>INH+RFP+PZA+EB(SM)\u306e4\u5264\u4f75\u7528\u3067\u5316\u5b66\u7642\u6cd5\u3092\u958b\u59cb\u3059\u308b\u3002\u611f\u53d7\u6027\u83cc\u3068\u5224\u660e\u3057\u305f\u3089\u4e0a\u8a18\u6cbb\u7642\u3092\u8a082\u30f5\u6708\u9593\u7d99\u7d9a\u3057\u3001\u4ee5\u5f8cINH+RFP\u30674\u30f5\u6708\u6cbb\u7642\u7d99\u7d9a\u3059\u308b\u3002PZA\u304c\u4f7f\u7528\u4e0d\u53ef\u306e\u5834\u5408\u306f\u3001INH+RFP+EB(SM)\u306e3\u5264\u4f75\u7528\u30672\u30f5\u6708\u9593\u6cbb\u7642\u5f8c\u3001INH+RFP\u30677\u30f5\u6708\u6cbb\u7642\u7d99\u7d9a\u3059\u308b\u3002<\/li>\n<\/ul>\n<\/li>\n<li>\u591a\u5264\u8010\u6027\u83cc\u3068\u5224\u660e\u6642\n<ul>\n<li>\u901f\u3084\u304b\u306b\u7d50\u6838\u5c02\u9580\u65bd\u8a2d\u3078\u642c\u9001\u3059\u308b\u304b\u3001\u5c02\u9580\u533b\u3068\u6cbb\u7642\u65b9\u91dd\u3092\u76f8\u8ac7\u3059\u308b\u3002\n<ol>\n<li>\u611f\u53d7\u6027\u306e\u6b8b\u3063\u305f\u85ac\u5264\u3092\u5e8f\u5217\u306b\u5f93\u3063\u30664\u5264\u4ee5\u4e0a\u9078\u629e\u3057\u540c\u6642\u306b\u6295\u4e0e\u3059\u308b\u3002\u6cbb\u7642\u671f\u9593\u306f\u83cc\u9670\u6027\u5316\u5f8c24\u30f6\u6708\u9593\u3002\u9ad8\u7528\u91cf\u30e2\u30ad\u30b7\u30d5\u30ed\u30ad\u30b5\u30b7\u30f3\u3092\u4f7f\u7528\u3059\u308b\u65b9\u6cd5\u3082\u3042\u308b\u3002<\/li>\n<li>\u9650\u5c40\u6027\u75c5\u5909\u3067\u3042\u308c\u3070\u5916\u79d1\u7684\u6cbb\u7642\u3082\u8003\u616e\u3059\u308b\u3002<\/li>\n<li>\u65b0\u898f\u6297\u7d50\u6838\u85ac\u306f\u9069\u683c\u6027\u8a8d\u5b9a\u30b7\u30b9\u30c6\u30e0\u306b\u627f\u8a8d\u3055\u308c\u305f\u533b\u7642\u6a5f\u95a2\u3067\u4f7f\u7528\u53ef\u80fd\u3067\u3042\u308b\u3002<\/li>\n<\/ol>\n<\/li>\n<li>\u6f5c\u5728\u6027\u7d50\u6838\u75c7<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<p style=\"text-align: right\">2019\u5e749\u670830\u65e5 19\u664254\u5206 \u6539\u8a02<\/p>\n<p>&nbsp;<\/p>\n<h2>\u30d0\u30a4\u30aa\u30c6\u30ed\u304c\u7591\u308f\u308c\u308b\u72b6\u6cc1\u3068\u5bfe\u5fdc<\/h2>\n<p><a href=\"https:\/\/h-crisis.niph.go.jp\/bt\/wp-content\/uploads\/sites\/3\/2019\/09\/\u30d0\u30a4\u30aa\u30c6\u30ed\u304c\u7591\u308f\u308c\u308b\u72b6\u6cc1MDRTB-1.png\"><img loading=\"lazy\" class=\"alignnone wp-image-854\" src=\"https:\/\/h-crisis.niph.go.jp\/bt\/wp-content\/uploads\/sites\/3\/2019\/09\/\u30d0\u30a4\u30aa\u30c6\u30ed\u304c\u7591\u308f\u308c\u308b\u72b6\u6cc1MDRTB-1-241x300.png\" alt=\"\" width=\"445\" height=\"554\" srcset=\"https:\/\/h-crisis.niph.go.jp\/bt\/wp-content\/uploads\/sites\/3\/2019\/09\/\u30d0\u30a4\u30aa\u30c6\u30ed\u304c\u7591\u308f\u308c\u308b\u72b6\u6cc1MDRTB-1-241x300.png 241w, https:\/\/h-crisis.niph.go.jp\/bt\/wp-content\/uploads\/sites\/3\/2019\/09\/\u30d0\u30a4\u30aa\u30c6\u30ed\u304c\u7591\u308f\u308c\u308b\u72b6\u6cc1MDRTB-1-768x958.png 768w, https:\/\/h-crisis.niph.go.jp\/bt\/wp-content\/uploads\/sites\/3\/2019\/09\/\u30d0\u30a4\u30aa\u30c6\u30ed\u304c\u7591\u308f\u308c\u308b\u72b6\u6cc1MDRTB-1-821x1024.png 821w, https:\/\/h-crisis.niph.go.jp\/bt\/wp-content\/uploads\/sites\/3\/2019\/09\/\u30d0\u30a4\u30aa\u30c6\u30ed\u304c\u7591\u308f\u308c\u308b\u72b6\u6cc1MDRTB-1.png 1452w\" sizes=\"(max-width: 445px) 100vw, 445px\" \/><\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u30b5\u30de\u30ea\u30fc \u00a0\u75c5\u539f\u4f53\u306e\u7279\u5fb4 \u539f\u56e0\u75c5\u539f\u4f53\uff1a\u7d50\u6838\u83cc\uff08Mycobacterium tuberculosis\uff09 \u6297\u9178\u83cc\u5c5e\u3001\u7d50\u6838\u83cc\u7fa4\u3000\u504f\u6027\u597d\u6c17\u6027\u83cc\u3001\u30b0\u30e9\u30e0\u967d\u6027\u687f\u83cc \u6297\u9178\u83cc\u67d3\u8272\u3067\u8d64\u6a59\u8272\u306e\u687f\u83cc\u3001\u9178\u30fb\u30a2\u30eb\u30ab\u30ea\u306b\u62b5\u6297\u6027 \u5206\u985e\u3068\u6f5c\u4f0f\u671f\u9593 \u611f\u67d3\u2026 <span class=\"read-more\"><a href=\"https:\/\/h-crisis.niph.go.jp\/bt\/disease\/14summary\/\">\u7d9a\u304d\u3092\u8aad\u3080 &raquo;<\/a><\/span><\/p>\n","protected":false},"author":12,"featured_media":0,"parent":32,"menu_order":14,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/h-crisis.niph.go.jp\/bt\/wp-json\/wp\/v2\/pages\/132"}],"collection":[{"href":"https:\/\/h-crisis.niph.go.jp\/bt\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/h-crisis.niph.go.jp\/bt\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/h-crisis.niph.go.jp\/bt\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/h-crisis.niph.go.jp\/bt\/wp-json\/wp\/v2\/comments?post=132"}],"version-history":[{"count":6,"href":"https:\/\/h-crisis.niph.go.jp\/bt\/wp-json\/wp\/v2\/pages\/132\/revisions"}],"predecessor-version":[{"id":1117,"href":"https:\/\/h-crisis.niph.go.jp\/bt\/wp-json\/wp\/v2\/pages\/132\/revisions\/1117"}],"up":[{"embeddable":true,"href":"https:\/\/h-crisis.niph.go.jp\/bt\/wp-json\/wp\/v2\/pages\/32"}],"wp:attachment":[{"href":"https:\/\/h-crisis.niph.go.jp\/bt\/wp-json\/wp\/v2\/media?parent=132"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}