{"id":282,"date":"2016-04-14T00:43:13","date_gmt":"2016-04-13T15:43:13","guid":{"rendered":"http:\/\/h-crisis.niph.go.jp\/bt\/?page_id=282"},"modified":"2023-10-24T15:33:40","modified_gmt":"2023-10-24T06:33:40","slug":"7detail","status":"publish","type":"page","link":"https:\/\/h-crisis.niph.go.jp\/bt\/disease\/7summary\/7detail\/","title":{"rendered":"\u8a73\u7d30\u30fc\u9f3b\u75bd\u30fb\u985e\u9f3b\u75bd"},"content":{"rendered":"<h3>\u75c5\u539f\u4f53\u306e\u7279\u5fb4<\/h3>\n<p>\u9f3b\u75bd\u83cc\u3001\u985e\u9f3b\u75bd\u83cc\u3001\u3044\u305a\u308c\u3082\u751f\u7269\u5175\u5668\u3078\u306e\u5fdc\u7528\u3092\u76ee\u7684\u306b\u7814\u7a76\u304c\u884c\u308f\u308c\u305f\u904e\u53bb\u304c\u3042\u308a\u3001\u7c73\u56fd\uff23\uff24\uff23\u306f\u30d0\u30a4\u30aa\u30c6\u30ed\u76ee\u7684\u3067\u4f7f\u7528\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u3044\u83cc\u3068\u3057\u3066\u3001\u3053\u306e2\u3064\u306e\u83cc\u3092\u30ab\u30c6\u30b4\u30ea\u30fc\uff22\u306b\u5206\u985e\u3057\u3066\u3044\u308b\u3002<\/p>\n<p>\u9f3b\u75bd\u83cc\u3001\u985e\u9f3b\u75bd\u83cc\u3068\u3082\u306b\u6771\u5357\u30a2\u30b8\u30a2\u3001\u30a2\u30d5\u30ea\u30ab\u3001\u4e2d\u6771\u5730\u57df\u306a\u3069\u306e\u71b1\u5e2f\u30fb\u4e9c\u71b1\u5e2f\u5730\u57df\u306b\u5206\u5e03\u3057\u3066\u304a\u308a\u3001\u81ea\u7136\u611f\u67d3\u306e\u4f8b\u304c\u3053\u308c\u3089\u306e\u5730\u57df\u306b\u304a\u3044\u3066\u6563\u767a\u7684\u306b\u767a\u751f\u3057\u3066\u3044\u308b\u3002<\/p>\n<p>\u9f3b\u75bd\u83cc\u3001\u985e\u9f3b\u75bd\u83cc\u3001\u3044\u305a\u308c\u3082\u611f\u67d3\u75c7\u6cd5\u306b\u3066\uff14\u985e\u611f\u67d3\u75c7\u306b\u5206\u985e\u3055\u308c\u3066\u304a\u308a\u3001\u8a3a\u65ad\u5f8c\u76f4\u3061\u306b\u6700\u5bc4\u308a\u306e\u4fdd\u5065\u6240\u306b\u5c4a\u51fa\u3092\u884c\u3046\u7fa9\u52d9\u304c\u3042\u308b\u3002<\/p>\n<h4>\u9f3b\u75bd<\/h4>\n<p>\u9f3b\u75bd\u306f\u9f3b\u75bd\u83cc (<i>Burkholderia mallei<\/i>) \u304c\u611f\u67d3\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u8d77\u3053\u308b\u4eba\u7363\u5171\u901a\u611f\u67d3\u75c7\u3067\u3042\u308b\u3002\u672c\u83cc\u306f\u30b0\u30e9\u30e0\u9670\u6027\u306e\u597d\u6c17\u6027\u687f\u83cc\u3067\u3001\u97ad\u6bdb\u3092\u3082\u305f\u305a\u904b\u52d5\u6027\u306f\u306a\u3044\u3002\u672c\u83cc\u306e\u767a\u80b2\u306f\u7de9\u5f90\u3067\u300141\u2103\u3067\u306f\u767a\u80b2\u3059\u308b\u304c\u300125\u2103\u4ee5\u4e0b\u3067\u306f\u767a\u80b2\u3057\u3065\u3089\u3044\u3002\u672c\u83cc\u306f\u304a\u3082\u306b\u99ac\u3084\u30ed\u30d0\u306b\u611f\u67d3\u3059\u308b\u304c\u3001\u3068\u304d\u306b\u30d2\u30c8\u306b\u3082\u611f\u67d3\u3059\u308b\u3002<\/p>\n<h4>\u985e\u9f3b\u75bd<\/h4>\n<p>\u985e\u9f3b\u75bd\u306f\u985e\u9f3b\u75bd\u83cc (<i>Burkholderia pseudomallei<\/i>)\u306b\u3088\u3063\u3066\u8d77\u3053\u308b\u4eba\u7363\u5171\u901a\u611f\u67d3\u75c7\u3067\u3042\u308b\u3002\u672c\u83cc\u306f<i>Whitmore<\/i>\u83cc\u3068\u3082\u547c\u3070\u308c\u3001\u597d\u6c17\u6027\u83cc\u306e\u30b0\u30e9\u30e0\u9670\u6027\u687f\u83cc\u3067\u3001\u97ad\u6bdb\u3092\u6709\u3057\u904b\u52d5\u6027\u3092\u793a\u3059\u3002\u571f\u58cc\u3084\u6c60\u306e\u6c34\u306a\u3069\u74b0\u5883\u4e2d\u304b\u3089\u985e\u9f3b\u75bd\u83cc\u304c\u5206\u96e2\u3055\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u3001\u5b9f\u969b\u306b\u571f\u3084\u6c34\u306e\u4e2d\u3067\u6570\u5e74\u9593\u751f\u5b58\u53ef\u80fd\u3068\u8a00\u308f\u308c\u3066\u3044\u308b\u3002<\/p>\n<p style=\"text-align: right\"><a title=\"\u9f3b\u75bd\u30fb\u985e\u9f3b\u75bd \u2013 Glanders, Melioidosis\uff08\u8a73\u7d30\uff09\" href=\"\/\/h-crisis.niph.go.jp\/bt\/disease\/7summary\/7detail\/\">\u25b2TOP<\/a><\/p>\n<h3>\u4e3b\u306a\u81e8\u5e8a\u50cf<\/h3>\n<h4>\u9f3b\u75bd<\/h4>\n<p>\u672c\u75be\u60a3\u306f\u81f4\u6b7b\u7684\u306a\u611f\u67d3\u304b\u3089\u6570\u5e74\u306b\u6e21\u308b\u6f5c\u4f0f\u611f\u67d3\u307e\u3067\u5e45\u5e83\u3044\u611f\u67d3\u3092\u5f15\u304d\u8d77\u3053\u3059\u3002\u9f3b\u75bd\u306e\u6025\u6027\u611f\u67d3\u4f8b\u3067\u306f1\uff5e14\u65e5\u9593\u306e\u6f5c\u4f0f\u671f\u3092\u7d4c\u3066\u767a\u75c7\u3059\u308b\u3002\u5178\u578b\u4f8b\u306b\u304a\u3051\u308b\u5c40\u6240\u75c7\u72b6\u306f\u5275\u90e8\u611f\u67d3\u3068\u6f70\u760d\u3001\u81bf\u760d\u3092\u4f34\u3046\u30ea\u30f3\u30d1\u7bc0\u708e\u3001\u9f3b\u7c98\u819c\u306a\u3069\u306e\u6f70\u760d\u3001\u591a\u95a2\u7bc0\u708e\u3001\u80ba\u708e\u3001\u80ba\u81bf\u760d\u304a\u3088\u3073\u7d50\u7bc0\u6027\u81bf\u760d\u306a\u3069\u3067\u3042\u308b\u3002\u58ca\u6b7b\u6027\u306e\u76ae\u819a\u306e\u767a\u75b9\u304c\u5168\u8eab\u611f\u67d3\u306e\u969b\u306b\u8a8d\u3081\u3089\u308c\u308b\u3068\u8a00\u308f\u308c\u3066\u3044\u308b\u3002\u307e\u305f\u6162\u6027\u5316\u81bf\u6027\u611f\u67d3\u306e\u30bf\u30a4\u30d7\u3067\u306f\u3001\u591a\u767a\u6027\u306e\u76ae\u4e0b\u3001\u7b4b\u8089\u3001\u304a\u3088\u3073\u5185\u81d3\u306e\u81bf\u760d\u3092\u4f34\u3046\u3002<\/p>\n<p>\u30d0\u30a4\u30aa\u30c6\u30ed\u3068\u3057\u3066\u9f3b\u75bd\u83cc\u304c\u5674\u9727\u3055\u308c\u305f\u5834\u5408\u3001\uff12\u9031\u9593\u4ee5\u5185\u306e\u6f5c\u4f0f\u671f\u3092\u7d4c\u3066\u767a\u75c5\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u3002\u80ba\u578b\u306e\u5834\u5408\u3001\u6025\u6fc0\u306a\u80ba\u708e\u75c7\u72b6\u3092\u8a34\u3048\u308b\u75c7\u4f8b\u304c\u540c\u6642\u671f\u306b\u591a\u767a\u3059\u308b\u53ef\u80fd\u6027\u304c\u3042\u308a\u3001\u6557\u8840\u75c7\u578b\u306e\u611f\u67d3\u3092\u8d77\u3053\u3059\u3068\u3001\u9ad8\u71b1\u3001\u60aa\u5bd2\u3001\u30b7\u30e7\u30c3\u30af\u306a\u3069\u306e\u75c7\u72b6\u3092\u4f34\u3044\u3001\u591a\u81d3\u5668\u4e0d\u5168\u306b\u9665\u308b\u306a\u3069\u91cd\u75c7\u611f\u67d3\u75c7\u4f8b\u304c\u540c\u6642\u671f\u306b\u96c6\u4e2d\u3057\u3066\u8a8d\u3081\u3089\u308c\u308b\u3002<\/p>\n<h4>\u985e\u9f3b\u75bd<\/h4>\n<p>\u81ea\u7136\u611f\u67d3\u306b\u304a\u3051\u308b\u985e\u9f3b\u75bd\u306f\u3001\u6025\u6027\u30fb\u6162\u6027\uff0c\u5c40\u6240\u6027\u30fb\u5168\u8eab\u6027\u3001\u3055\u3089\u306b\u9855\u6027\u30fb\u4e0d\u9855\u6027\u306e\u5e83\u3044\u7bc4\u56f2\u306e\u611f\u67d3\u5f62\u614b\u304b\u3089\u6210\u308a\u7acb\u3063\u3066\u3044\u308b\u3002\u306a\u304a\u985e\u9f3b\u75bd\u306f\u83cc\u8840\u75c7\u30fb\u6025\u6027\u6557\u8840\u75c7\u578b\u3001\u80ba\u578b\u3001\u5c40\u6240\u578b\u3001\u304a\u3088\u3073\u4e0d\u9855\u6027\u578b\u306e\uff14\u7a2e\u985e\u306e\u75c5\u578b\u306b\u5206\u3051\u3089\u308c\u308b\u3002<br \/>\n\u985e\u9f3b\u75bd\u306e\u5404\u75c5\u578b<\/p>\n<ol>\n<li>\u83cc\u8840\u75c7\u578b\u307e\u305f\u306f\u6025\u6027\u6557\u8840\u75c7\u578b\n<ul>\n<li>\u7d4c\u904e\uff1a\u6025\u6fc0\u306b\u5168\u8eab\u611f\u67d3\u72b6\u614b\u3068\u306a\u308b<\/li>\n<li>\u4e3b\u306a\u75c7\u72b6\uff1a\u767a\u71b1\uff0c\u60aa\u5bd2\uff0c\u30b7\u30e7\u30c3\u30af<\/li>\n<li>\u4e88\u5f8c\uff1a\u4e0d\u826f\uff08\u81f4\u6b7b\u7387\u306f\u9ad8\u3044\uff09<\/li>\n<\/ul>\n<\/li>\n<li>\u80ba\u578b\n<ul>\n<li>\u7d4c\u904e\uff1a\u6025\u6fc0\u306a\u767a\u75c7<\/li>\n<li>\u4e3b\u306a\u75c7\u72b6\uff1a\u767a\u71b1\uff0c\u54b3\u55fd\u3001\u5580\u75f0\u3001\u8840\u75f0<\/li>\n<li>\u4e88\u5f8c\uff1a\u9069\u5207\u306a\u6cbb\u7642\u3092\u53d7\u3051\u308c\u3070\u826f\u597d<\/li>\n<li>\u5c40\u6240\u578b<\/li>\n<li>\u7d4c\u904e\uff1a\u7de9\u5f90<\/li>\n<li>\u4e3b\u306a\u75c7\u72b6\uff1a\u5c40\u6240\u306e\u816b\u8139\uff0c\u305d\u306e\u4ed6<\/li>\n<li>\u4e88\u5f8c\uff1a\u9069\u5207\u306a\u6cbb\u7642\u3092\u53d7\u3051\u308c\u3070\u826f\u597d<\/li>\n<\/ul>\n<\/li>\n<li>\u4e0d\u9855\u6027\u578b\n<ul>\n<li>\u8840\u6e05\u5b66\u7684\u8a3a\u65ad\u306b\u3088\u3063\u3066\u5224\u5b9a<\/li>\n<li>\u6d78\u6deb\u5730\u57df\u3067\u306f1\uff5e3%\u7a0b\u5ea6\u306b\u967d\u6027<\/li>\n<\/ul>\n<\/li>\n<\/ol>\n<h5>\u83cc\u8840\u75c7\u578b\u307e\u305f\u306f\u6025\u6027\u6557\u8840\u75c7\u578b<\/h5>\n<p>5\uff5e10\u65e5\u9593\u306e\u6f5c\u4f0f\u671f\u306e\u5f8c\u3001\u6025\u6027\u306e\u5168\u8eab\u611f\u67d3\u3092\u5f15\u304d\u8d77\u3053\u3059\u3002\u3044\u3063\u305f\u3093\u767a\u75c7\u3059\u308b\u3068\u3001\u767a\u71b1\u3001\u60aa\u5bd2\u3068\u3068\u3082\u306b\u30b7\u30e7\u30c3\u30af\u72b6\u614b\u306b\u9665\u308a\u3084\u3059\u3044\u3002\u5c40\u6240\u6240\u898b\u3092\u8a8d\u3081\u308b\u3053\u3068\u306f\u5c11\u306a\u3044\u304c\u3001\u6642\u306b\u80f8\u75db\u3001\u76ae\u819a\u81bf\u760d\u3001\u30ea\u30f3\u30d1\u7bc0\u816b\u8139\u3001\u306a\u3069\u306e\u6240\u898b\u3092\u5448\u3059\u308b\u3002\u672c\u75c5\u578b\u306e\u4e88\u5f8c\u306f\u60aa\u304f\u3001\u81f4\u6b7b\u7387\u306f\u9ad8\u3044\u3002\u305f\u3068\u3048\u6297\u83cc\u85ac\u306e\u6295\u4e0e\u3092\u53d7\u3051\u305f\u5834\u5408\u3067\u3082\u75c5\u72b6\u306e\u6539\u5584\u3092\u8a8d\u3081\u306a\u3044\u75c7\u4f8b\u3082\u591a\u3044\u3068\u8a00\u308f\u308c\u3066\u3044\u308b\u3002<\/p>\n<h5>\u80ba\u578b<\/h5>\n<p>\u985e\u9f3b\u75bd\u306e\u4e2d\u3067\u306f\u3053\u306e\u75c5\u578b\u304c\u5360\u3081\u308b\u5272\u5408\u304c\u9ad8\u3044\u3002\u6025\u6027\u671f\u306e\u547c\u5438\u5668\u611f\u67d3\u3092\u8d77\u3053\u3059\u3068\u6c17\u7ba1\u652f\u708e\u3001\u80ba\u708e\u3092\u767a\u75c7\u3059\u308b\u3002\u6570\u9031\u9593\u306e\u6f5c\u4f0f\u671f\u306e\u5f8c\u3001\u767a\u71b1\u3001\u54b3\u55fd\u3001\u5580\u75f0\u3001\u8840\u75f0\u3001\u306a\u3069\u306e\u75c7\u72b6\u304c\u51fa\u73fe\u3059\u308b\u3002\u80f8\u90e8\uff38\u7dda\u306b\u3066\u7a7a\u6d1e\u3092\u4f34\u3046\u9670\u5f71\u304c\u8a8d\u3081\u3089\u308c\u308b\u3053\u3068\u304c\u591a\u3044\u3002<\/p>\n<h5>\u5c40\u6240\u578b<\/h5>\n<p>\u985e\u9f3b\u75bd\u3067\u306f\u8af8\u81d3\u5668\u306b\u5c0f\u81bf\u760d\u3092\u5f62\u6210\u3057\u3001\u591a\u69d8\u306a\u75c7\u72b6\u3092\u793a\u3059\u3002 \u5c40\u6240\u75c5\u5909\u3068\u3057\u3066\u306f\u611f\u67d3\u5c40\u6240\u306b\u7d50\u7bc0\u3001\u30ea\u30f3\u30d1\u7ba1\u708e\u3001\u30ea\u30f3\u30d1\u7bc0\u708e\u3092\u8d77\u3053\u3059\u3002\u3053\u306e\u81bf\u760d\u306f\u7d4c\u904e\u304c\u7de9\u5f90\u3067\u3042\u308a\u3001\u7d50\u6838\u6027\u306e\u81bf\u760d\u306a\u3069\u3068\u306e\u9451\u5225\u304c\u56f0\u96e3\u306a\u5834\u5408\u304c\u591a\u304f\u3001\u5207\u9664\u5f8c\u306b\u521d\u3081\u3066\u8a3a\u65ad\u304c\u306a\u3055\u308c\u308b\u5834\u5408\u3082\u3042\u308b\u3002\u6162\u6027\u671f\u306e\u75c5\u5909\u306f\u76ae\u819a\u3001\u81bf\u3001\u80ba\u3001\u5fc3\u7b4b\u3001\u809d\u3001\u813e\u3001\u524d\u7acb\u817a\u3001\u9aa8\u3001\u95a2\u7bc0\u3001\u30ea\u30f3\u30d1\u7bc0\u3001\u76ee\u306a\u3069\u3055\u307e\u3056\u307e\u306a\u90e8\u4f4d\u306b\u81bf\u760d\u304c\u8a8d\u3081\u3089\u308c\u308b\u3002<\/p>\n<h5>\u4e0d\u9855\u6027\u578b<\/h5>\n<p>\u30d2\u30c8\u306e\u985e\u9f3b\u75bd\u3067\u306f\u7121\u75c7\u5019\u306e\u72b6\u614b\u3067\u3068\u304d\u306b\u6570\u5e74\u9593\u3082\u306e\u9593\u3001\u6162\u6027\u306e\u611f\u67d3\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u304c\u3042\u308b\u3002\u6162\u6027\u611f\u67d3\u306b\u304a\u3044\u3066\u306f\u6570\u5e74\u9593\u7d4c\u904e\u3057\u305f\u5f8c\u3067\u518d\u767a\u3059\u308b\u4f8b\u304c\u3042\u308a\u3001\u514d\u75ab\u80fd\u306e\u4f4e\u4e0b\u304c\u767a\u75c7\u306e\u8a98\u56e0\u306b\u306a\u308b\u3068\u8003\u3048\u3089\u308c\u3066\u3044\u308b\u3002\u611f\u67d3\u9632\u5fa1\u80fd\u304c\u4f4e\u4e0b\u3057\u3066\u3044\u308b\u3088\u3046\u306a\u75c7\u4f8b\u304c\u672c\u83cc\u306b\u611f\u67d3\u3059\u308b\u3068\u91cd\u7be4\u306a\u7d4c\u904e\u3092\u53d6\u308b\u3053\u3068\u304c\u591a\u3044\u3002\u306a\u304a\u672c\u75be\u60a3\u306e\u30bf\u30a4\u3001\u30d9\u30c8\u30ca\u30e0\u3001\u30de\u30ec\u30fc\u30b7\u30a2\u306e\u6d78\u6deb\u5730\u57df\u306b\u304a\u3051\u308b\u75ab\u5b66\u7684\u8abf\u67fb\u3067\u306f\u3001\u5bfe\u8c61\u4f4f\u6c11\u306e\uff11\uff5e\uff13%\uff08\u4e00\u90e8\u306b\u306f\uff16\uff5e\uff18%\uff09\u304c\u6297\u4f53\u967d\u6027\u3067\u3042\u3063\u305f\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002<\/p>\n<p style=\"text-align: right\"><a title=\"\u9f3b\u75bd\u30fb\u985e\u9f3b\u75bd \u2013 Glanders, Melioidosis\uff08\u8a73\u7d30\uff09\" href=\"\/\/h-crisis.niph.go.jp\/bt\/disease\/7summary\/7detail\/\">\u25b2TOP<\/a><\/p>\n<h3>\u81e8\u5e8a\u691c\u67fb\u6240\u898b<\/h3>\n<h4>\u8840\u6db2\u751f\u5316\u5b66\u691c\u67fb<\/h4>\n<p>\u9f3b\u75bd\u3001\u985e\u9f3b\u75bd\u3068\u3082\u306b\u8840\u7b97\u3067\u306f\u8efd\u5ea6\u304b\u3089\u4e2d\u7b49\u5ea6\u306e\u767d\u8840\u7403\u6570\u5897\u52a0\u3092\u8a8d\u3081\u3001\u6838\u306e\u5de6\u65b9\u79fb\u52d5\u3092\u4f34\u3046\u3002\u672c\u75be\u60a3\u306b\u7279\u5fb4\u7684\u306a\u751f\u5316\u5b66\u7684\u6240\u898b\u306f\u8a8d\u3081\u306a\u3044\u3002<\/p>\n<h4>\u753b\u50cf\u691c\u67fb\u305d\u306e\u4ed6<\/h4>\n<p>\u9f3b\u75bd\u3001\u985e\u9f3b\u75bd\u3068\u3082\u306b\u80f8\u90e8X\u7dda\u306b\u3066\u4e21\u5074\u6027\u306e\u6c17\u7ba1\u652f\u80ba\u708e\u3001\u7c9f\u7c92\u6027\u306e\u7d50\u7bc0\u3001\u533a\u57df\u6027\u3042\u308b\u3044\u306f\u80ba\u8449\u6027\u306e\u6d78\u6f64\u5f71\u3001\u7a7a\u6d1e\u6027\u306e\u5909\u5316\u306a\u3069\u3055\u307e\u3056\u307e\u306a\u6240\u898b\u304c\u8a8d\u3081\u3089\u308c\u308b\u3002\u307e\u305f\u80f8\u6c34\u8caf\u7559\u3092\u4f34\u3046\u5834\u5408\u3082\u3042\u308b\u3002\u8179\u90e8\u8d85\u97f3\u6ce2\u691c\u67fb\u3084CT\u3067\u306f\u3001\u6df1\u90e8\u81bf\u760d\u3092\u8a8d\u3081\u308b\u3002\u306a\u304a\u985e\u9f3b\u75bd\u3067\u306f\u3068\u304d\u306b\u7121\u75c7\u5019\u6027\u306e\u80ba\u611f\u67d3\u304c\u3001\u80f8\u90e8X\u7dda\u306e\u9670\u5f71\u3092\u304d\u3063\u304b\u3051\u3068\u3057\u3066\u767a\u898b\u3055\u308c\u308b\u4f8b\u304c\u3042\u308b\u3002<\/p>\n<p style=\"text-align: right\"><a title=\"\u9f3b\u75bd\u30fb\u985e\u9f3b\u75bd \u2013 Glanders, Melioidosis\uff08\u8a73\u7d30\uff09\" href=\"\/\/h-crisis.niph.go.jp\/bt\/disease\/7summary\/7detail\/\">\u25b2TOP<\/a><\/p>\n<h3>\u78ba\u5b9a\u8a3a\u65ad<\/h3>\n<p>\u56fd\u7acb\u611f\u67d3\u75c7\u7814\u7a76\u6240\u306e\u30a6\u30a7\u30d6\u30b5\u30a4\u30c8\u306b\u3066<a href=\"https:\/\/www.niid.go.jp\/niid\/ja\/labo-manual.html\">\u75c5\u539f\u4f53\u30de\u30cb\u30e5\u30a2\u30eb<\/a>\u304c\u516c\u958b\u3055\u308c\u3066\u3044\u308b\u3002<\/p>\n<h4>\u691c\u4f53\u306e\u63a1\u53d6\u3001\u8f38\u9001\u3001\u4fdd\u5b58\u306a\u3069<\/h4>\n<p>\u78ba\u5b9a\u8a3a\u65ad\u306f\u57f9\u990a\u306b\u3088\u308b\u83cc\u306e\u5206\u96e2\u30fb\u540c\u5b9a\u306b\u3088\u3063\u3066\u884c\u308f\u308c\u308b\u3002\u691c\u4f53\u3068\u3057\u3066\u306f\u8840\u6db2\u3001\u5580\u75f0\u304a\u3088\u3073\u81bf\u5206\u6ccc\u7269\uff08\u7a7f\u523a\u691c\u4f53\u3001\u305d\u306e\u4ed6\uff09\u306a\u3069\u3092\u7528\u3044\u308b\u3002<\/p>\n<p>\u8840\u6e05\u5b66\u7684\u8a3a\u65ad\u6cd5\u3092\u76ee\u7684\u3068\u3057\u3066\u8840\u6e05\u3092\u63a1\u53d6\u3059\u308b\u304c\u3001\u9f3b\u75bd\u3068\u985e\u9f3b\u75bd\u3067\u306f\u4ea4\u53c9\u53cd\u5fdc\u306e\u53ef\u80fd\u6027\u304c\u6307\u6458\u3055\u308c\u3066\u304a\u308a\u3001\u9451\u5225\u304c\u56f0\u96e3\u306a\u5834\u5408\u304c\u3042\u308b\u3002<\/p>\n<p>\u9f3b\u75bd\u83cc<i>B. mallei<\/i>\u3068\u985e\u9f3b\u75bd\u83cc<i>B. pseudomallei<\/i>\u306f\u571f\u58cc\u3084\u6c34\u7530\u3067\u751f\u606f\u3059\u308b\u7d30\u83cc\u3067\u3001\u4f4e\u6804\u990a\u72b6\u614b\u3067\u3082\u9577\u671f\u9593\u751f\u5b58\u3057\u3001\u4e7e\u71e5\u306b\u3082\u5f37\u3044\u3002\u6db2\u4f53\u57f9\u5730\u3067\u306f <i>Burkholderia<\/i>\u5c5e\u306e\u4ed6\u306e\u7d30\u83cc\u306f\u6db2\u4f53\u57f9\u5730\u3084\u56fa\u5f62\u57f9\u5730\u3067\u6570\u65e5\u3067\u6025\u901f\u306b\u5897\u6b96\u3057\u3066\u81ea\u5df1\u878d\u89e3\u3057\u3001\u6b7b\u6ec5\u3059\u308b\u304c\u3001\u3053\u306e\u83cc\u306f\u6570\u9031\u9593\u3067\u3082\u57f9\u5730\u304b\u3089\u76db\u308a\u4e0a\u304c\u3063\u3066\u5897\u6b96\u3092\u7d9a\u3051\u308b\u3002\u7279\u306b\u985e\u9f3b\u75bd\u83cc\u306e\u5897\u6b96\u529b\u306f\u5f37\u3044\u3002\u4eba\u306e\u611f\u67d3\u75c7\u306e\u5834\u5408\u3001\u76ae\u819a\u81bf\u760d\u3001\u9aa8\u9ac4\u3001\u8840\u6db2\u3001\u80ba\u708e\u306e\u6d17\u6d44\u6db2\u306a\u3069\u304c\u6750\u6599\u3068\u306a\u308b\u304c\u3001\u7279\u5225\u306a\u9078\u629e\u57f9\u5730\u306f\u958b\u767a\u3055\u308c\u3066\u3044\u306a\u3044\u3002<\/p>\n<p>\u666e\u901a\u5bd2\u5929\u3001Brain Heart infusion\u5bd2\u5929\u57f9\u5730\u3001\u8840\u6db2\u57f9\u5730\u3044\u305a\u308c\u3067\u3082\u826f\u597d\u306b\u767a\u80b2\u3059\u308b\u3002\u80ba\u708e\u306e\u60a3\u8005\u306e\u5580\u75f0\u304b\u3089\u9078\u629e\u5206\u96e2\u3059\u308b\u57f9\u5730\u306f\u958b\u767a\u3055\u308c\u3066\u3044\u306a\u3044\u3002\u63a1\u53d6\u3057\u305f\u6750\u6599\u306f\u597d\u6c17\u6761\u4ef6\u3067\u5ba4\u6e29\u3001\u4f4e\u6e29\u306e\u3044\u305a\u308c\u3067\u3082\u8f38\u9001\u3057\u3066\u3082\u304b\u307e\u308f\u306a\u3044\u3002\u5178\u578b\u7684\u306a\u76ba\u306e\u3088\u3063\u305f\u96c6\u843d\u306f \u8840\u6db2\u5bd2\u5929\u3067\u3082\u89b3\u5bdf\u3067\u304d\u308b\u5834\u5408\u304c\u3042\u308b\u304c\u300110%\u30b0\u30ea\u30bb\u30ed\u30fc\u30eb\u304c\u306f\u3044\u3063\u305f Brain Heart infusion\u57f9\u5730\u306b\u63a5\u7a2e\u3059\u308c\u3070\uff08<a href=\"\/\/h-crisis.niph.go.jp\/bt\/wp-content\/uploads\/sites\/3\/2016\/04\/img_20091105091112.jpg\" target=\"_blank\" rel=\"noopener noreferrer\">\u56f31<\/a>\uff09\uff12\uff0d\uff13\u65e5\u3067\u7279\u8272\u306e\u3042\u308b\u96c6\u843d\u306b\u304b\u308f\u308b\u3002\u4e00\u65b9\u3001 <i>B. mallei<\/i>\u306e\u767a\u80b2\u306f\u9045\u304f\u3001\u5c0f\u3055\u306a\u5e73\u6ed1\u306a\u96c6\u843d\u3092\u4f5c\u308b\u3002\u4ed6\u306e <i>Burkholderia<\/i>\u5c5e\u306e\u83cc\u7a2e\u3068\u96c6\u843d\u306e\u7279\u5fb4\u7684\u306a\u5dee\u7570\u306f\u898b\u3089\u308c\u306a\u3044\u3002<\/p>\n<p><i>B. pseudomallei<\/i>\u3092\u571f\u58cc\u304b\u3089\u5206\u96e2\u3059\u308b\u306b\u306f\u53e4\u304f\u304b\u3089 Ashdown\u306e\u9078\u629e\u57f9\u5730\u304c\u4f7f\u7528\u3055\u308c\u3066\u3044\u308b\u3002<\/p>\n<ul>\n<li>\u84b8\u7559\u6c34\uff1a475 ml<\/li>\n<li>\u5bd2\u5929\uff08No.2\u3001Oxoid\uff09:5 g<\/li>\n<li>\u52a0\u6e29\u3057\u305f\u30b0\u30ea\u30bb\u30ed\u30fc\u30eb\uff1a20 ml<\/li>\n<li>0.1% \u30af\u30ea\u30b9\u30bf\u30eb\u30d0\u30a4\u30aa\u30ec\u30c3\u30c8\uff1a2.5 ml<\/li>\n<li>1.0%\u30cb\u30e5\u30fc\u30c8\u30e9\u30eb\u30ec\u30c3\u30c9\uff1a2.5 ml<\/li>\n<\/ul>\n<p>\u6ec5\u83cc\u5f8c\u300156\u2103\u306b\u4fdd\u3061\u30b2\u30f3\u30bf\u30de\u30a4\u30b7\u30f3(1mg\/ml)\u30922.5 ml\u52a0\u3048\u3001\u5e73\u677f\u3092\u4f5c\u6210\u3059\u308b\u3002\u4f5c\u6210\u5f8c\u30014\u2103\u4fdd\u5b58\u3001\u4e00\u9031\u9593\u306f\u4f7f\u7528\u3067\u304d\u308b\u3002\u3053\u306e\u4f4e\u6804\u990a\u57f9\u5730\u3067\uff13\u301c\uff14\u65e5\u3067\u5c0f\u3055\u306a\u7c98\u6027\u306e\u3042\u308b\u96c6\u843d\u3092\u4f5c\u308b\u3002\u57f9\u5730\u4e0a\u3067\u306f <i>B. pseudomallei<\/i>\u306f\u900f\u660e\u306e\u96c6\u843d\u306e\u4e2d\u5fc3\u306b\u8d64\u3044\u8272\u304c\u898b\u3048\u308b\u7279\u8272\u306e\u3042\u308b\u96c6\u843d\u3092\u5f62\u6210\u3059\u308b\uff08<a href=\"\/\/h-crisis.niph.go.jp\/bt\/wp-content\/uploads\/sites\/3\/2016\/04\/img_20091105092408.jpg\" target=\"_blank\" rel=\"noopener noreferrer\">\u56f32<\/a>\uff09\u3002\u5580\u75f0\u304b\u3089\u306e\u9078\u629e\u5206\u96e2\u3068\u78ba\u8a8d\u306b\u5229\u7528\u3067\u304d\u308b\u53ef\u80fd\u6027\u304c\u3042\u308b\u304c\u3001\u81e8\u5e8a\u5fdc\u7528\u3057\u305f\u5831\u544a\u306f\u306a\u3044\u3002<\/p>\n<p>\u306a\u304a2003\u5e747\u6708\u306b\u7c73\u56fd\u30ed\u30b5\u30f3\u30bc\u30eb\u30b9\u5730\u57df\u306e\u81e8\u5e8a\u691c\u67fb\u5ba4\u306b\u304a\u3044\u3066\uff0c\u81e8\u5e8a\u691c\u4f53\u3088\u308a<i>B. pseudomallei<\/i>\u304c\u5206\u96e2\u3055\u308c\u3001\u691c\u67fb\u5ba4\u5185\u611f\u67d3\u306e\u7cbe\u67fb\u304c\u884c\u308f\u308c\u305f\u7d50\u679c\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002\u5e78\u3044\u3001\u66dd\u9732\u3055\u308c\u305f\u53ef\u80fd\u6027\u306e\u3042\u308b\u691c\u67fb\u6280\u5e2b\uff11\uff17\u540d\u306b\u5bfe\u3057\u3066\uff33\uff34\u5408\u5264\u306a\u3069\u306e\u4e88\u9632\u7684\u6297\u83cc\u85ac\u6295\u4e0e\u304c\u884c\u308f\u308c\u3001\u6700\u7d42\u7684\u306b\u611f\u67d3\u75c7\u767a\u75c7\u4f8b\u306f\u8a8d\u3081\u306a\u304b\u3063\u305f\u3002\u305f\u3060\u3057\u57f9\u990a\u30b7\u30e3\u30fc\u30ec\u3092\u3042\u3051\u3066\u81ed\u3044\u3092\u304b\u3044\u3060\u308a\u3001\u7d30\u83cc\u306e\u30a8\u30a2\u30ed\u30be\u30eb\u3092\u767a\u751f\u3059\u308b\u3088\u3046\u306a\u4f5c\u696d\u306f\u5371\u967a\u3067\u3042\u308b\u305f\u3081\u3001\u53ef\u80fd\u6027\u306e\u3042\u308b\u75c5\u539f\u4f53\u3068\u77e5\u3089\u305a\u66dd\u9732\u3055\u308c\u305f\u53ef\u80fd\u6027\u304c\u8003\u3048\u3089\u308c\u308b\u5834\u5408\u306b\u306f\uff0c\u6297\u83cc\u85ac\u306b\u3088\u308b\u4e88\u9632\u3092\u8003\u616e\u3059\u308b\u5fc5\u8981\u304c\u3042\u308b\u3002<\/p>\n<h4>\u7d30\u83cc\u5b66\u7684\u691c\u67fb\u6cd5<\/h4>\n<p><i>B. mallei<\/i>\u3068<i>B. pseudomallei<\/i>\u306f90%\u4ee5\u4e0a\u306eDNA\u306e\u985e\u4f3c\u5ea6\u304c\u3042\u308a\u3001\u5206\u985e\u5b66\u7684\u306b\u540c\u4e00\u7a2e\u3067\u3042\u308b\u3002\u3057\u304b\u3057 <i>B. mallei<\/i>\u306f\u9f3b\u75bd (Glander)\u3092<i>B. pseudomallei<\/i> \u306f\u985e\u9f3b\u75bd\uff08Melioidosis\uff09\u3068\u7570\u306a\u3063\u305f\u75c5\u614b\u3092\u5f15\u304d\u8d77\u3053\u3059\u3053\u3068\u304b\u3089\u3001\u53e4\u304f\u304b\u3089\u72ec\u7acb\u3057\u305f\u5225\u306e\u83cc\u7a2e\u3068\u3057\u3066\u4fe1\u3058\u3089\u308c\u3066\u304d\u305f\u3002\u4e21\u83cc\u7a2e\u3068\u3082\u30b2\u30ce\u30e0\u89e3\u6790\u304c\u7d42\u4e86\u3057\u3001<i>B. mallei<\/i>\u306f<i>B. pseudomallei<\/i>\u304c\u4fdd\u6301\u3057\u3066\u3044\u308b\u591a\u304f\u306e\u907a\u4f1d\u5b50\u304c\u8131\u843d\u3057\u3001\u9ad8\u5ea6\u306b\u5bb6\u755c\u306b\u5bc4\u751f\u3057\u9032\u5316\u3057\u3066\u304d\u305f\u3053\u3068\u304c\u8a3c\u660e\u3055\u308c\u305f\u3002<\/p>\n<p><i>B. mallei<\/i>\u306f\u904b\u52d5\u6027\u304c\u7121\u304f\u3001 <i>B. pseudomallei<\/i>\u306f\u97ad\u6bdb\u3092\u767a\u73fe\u3057\u904b\u52d5\u6027\u304c\u3042\u308b\u3002 <i>B. mallei<\/i> \u306f<i>B. pseudomallei<\/i>\u3068\u540c\u3058\u914d\u5217\u306e\u97ad\u6bdb\u907a\u4f1d\u5b50\u3092\u4fdd\u6709\u3059\u308b\u304c\u3001\u97ad\u6bdb\u3092\u767a\u73fe\u3057\u3066\u3044\u306a\u3044\u3002<i>B. pseudomallei<\/i>\u306f\u901a\u5e38\u306f\u4e9c\u71b1\u5e2f\u304b\u3089\u71b1\u5e2f\u5730\u65b9\u306e\u571f\u58cc\u3001\u6c34\u3092\u4e2d\u5fc3\u306b\u5730\u7403\u4e0a\u306b\u5e45\u5e83\u304f\u5206\u5e03\u3057\u3066\u3044\u308b\u304c\u3001 <i>B. mallei<\/i>\u306f\u9ad8\u5ea6\u306b\u52d5\u7269\u306b\u5bc4\u751f\u3057\u3001\u9032\u5316\u306e\u9014\u4e2d\u3067\u904b\u52d5\u6027\u3092\u5931\u3063\u305f\u3068\u63a8\u6e2c\u3055\u308c\u308b\u3002\u907a\u4f1d\u5b66\u7684\u306b\u540c\u4e00\u7a2e\u3067\u3042\u308b\u306b\u3082\u4fc2\u308f\u3089\u305a\u3001\u83cc\u306e\u96c6\u843d\u3001\u767a\u80b2\u30d1\u30bf\u30fc\u30f3\u306f\u5927\u304d\u304f\u7570\u306a\u308b\u3002\u7279\u5fb4\u7684\u306a\u96c6\u843d\u3068 \u30b0\u30e9\u30e0\u9670\u6027\u975e\u767a\u9175\u687f\u83cc\u3067\u3042\u308b <i>B. cepacia<\/i>\u306b\u8fd1\u3044\u7279\u5fb4\u3092\u6301\u3063\u3066\u3044\u308b\u306e\u3067\u751f\u5316\u5b66\u7684\u306b\u306f\u5bb9\u6613\u306b\u540c\u5b9a\u3067\u304d\u308b\u3002\u4f46\u3057\u30bf\u30a4\u306e\u571f\u58cc\u304b\u3089\u307f\u3064\u304b\u3063\u305f <i>B. thailandensis<\/i>\u306f\u751f\u5316\u5b66\u7684\u6027\u72b6\u304c\u985e\u4f3c\u3057\u3001\u9577\u5e74\u3001\u75c5\u539f\u6027\u306e\u306a\u3044 Arabinose\u5206\u89e3\u306e <i>B. pseudomallei<\/i> \u3068\u3057\u3066\u5831\u544a\u3055\u308c\u3066\u304d\u305f\u304c\u3001\u72ec\u7acb\u3057\u305f\u83cc\u7a2e\u3068\u3057\u3066\u5831\u544a\u3055\u308c\u308b\u3088\u3046\u306b\u306a\u3063\u305f\u3002 \u9451\u5225\u304c\u5fc5\u8981\u306a\u306e\u306f <i>B. cepacia<\/i>, <i>B. thailandensis<\/i>, <i>B. vietnamensis<\/i>\u306a\u3069\u306e\u985e\u7e01\u83cc\u3067\u3042\u308b\u3002\u751f\u5316\u5b66\u7684\u6027\u72b6\u3067\u306e\u9451\u5225\u70b9\u306f\u8868\uff11\u306b\u793a\u3057\u305f\u3002<\/p>\n<p>Melioidosis\u306e\u6cbb\u7642\u3067\u306f\u7d50\u6838\u3068\u540c\u3058\u304f\u521d\u671f\u306e\u96c6\u4e2d\u7642\u6cd5\u306b\u5931\u6557\u3059\u308b\u3068\u611f\u67d3\u304c\u6301\u7d9a\u3057\u6cbb\u7652\u304c\u56f0\u96e3\u306b\u306a\u308b\u306e\u3067\u83cc\u306e\u6b63\u78ba\u306a\u540c\u5b9a\u304c\u5fc5\u8981\u306b\u306a\u308b\u3002<\/p>\n<table border=\"0\">\n<tbody>\n<tr>\n<td>\n<table>\n<caption>\u8868\uff11 \u9f3b\u75bd\u83cc\u30fb\u985e\u9f3b\u75bd\u83cc \u3068\u985e\u7e01\u83cc\u3068\u306e\u9451\u5225<\/caption>\n<tbody>\n<tr>\n<td>\u8cc7\u5316\u30c6\u30b9\u30c8<\/td>\n<td><i>B. uboniae<\/i><\/td>\n<td><i>B. cepacia<\/i><\/td>\n<td><i>B. vietnamensis<\/i><\/td>\n<td><i>B. thailandensis<\/i><\/td>\n<td><i>B. mallei<\/i><\/td>\n<td><i>B. pseudomallei<\/i><\/td>\n<\/tr>\n<tr>\n<td>L(+)Arabinose<\/td>\n<td class=\"center\">\uff0b<\/td>\n<td class=\"center\">\uff0b<\/td>\n<td class=\"center\">\uff0b<\/td>\n<td class=\"center\">\uff0b<\/td>\n<td class=\"center\">\uff0d<\/td>\n<td class=\"center\">\uff0d<\/td>\n<\/tr>\n<tr>\n<td>D(+)Xylose<\/td>\n<td class=\"center\">\uff0b<\/td>\n<td class=\"center\">\uff0b<\/td>\n<td class=\"center\">\uff0b<\/td>\n<td class=\"center\">\uff0b<\/td>\n<td class=\"center\">\uff0d<\/td>\n<td class=\"center\">\uff0d<\/td>\n<\/tr>\n<tr>\n<td>Maltose<\/td>\n<td class=\"center\">\uff0b<\/td>\n<td class=\"center\">\uff0d<\/td>\n<td class=\"center\">\uff0d<\/td>\n<td class=\"center\">\uff0d<\/td>\n<td class=\"center\">\uff0d<\/td>\n<td class=\"center\">\uff0d<\/td>\n<\/tr>\n<tr>\n<td>D-glucronate<\/td>\n<td class=\"center\">\uff0b<\/td>\n<td class=\"center\">\uff0b<\/td>\n<td class=\"center\">\uff0b<\/td>\n<td class=\"center\">\uff0d<\/td>\n<td class=\"center\">\uff0d<\/td>\n<td class=\"center\">\uff0d<\/td>\n<\/tr>\n<tr>\n<td>D-galacturonate<\/td>\n<td class=\"center\">\uff0b<\/td>\n<td class=\"center\">\uff0b<\/td>\n<td class=\"center\">\uff0b<\/td>\n<td class=\"center\">\uff0d<\/td>\n<td class=\"center\">\uff0d<\/td>\n<td class=\"center\">\uff0d<\/td>\n<\/tr>\n<tr>\n<td>Histamine<\/td>\n<td class=\"center\">\uff0b<\/td>\n<td class=\"center\">\uff0b<\/td>\n<td class=\"center\">\uff0b<\/td>\n<td class=\"center\">\uff0d<\/td>\n<td class=\"center\">\uff0d<\/td>\n<td class=\"center\">\uff0d<\/td>\n<\/tr>\n<tr>\n<td>Dulcitol<\/td>\n<td class=\"center\">\uff0d<\/td>\n<td class=\"center\">\uff0b<\/td>\n<td class=\"center\">\uff0b<\/td>\n<td class=\"center\">\uff0b<\/td>\n<td class=\"center\">\uff0b<\/td>\n<td class=\"center\">\uff0b<\/td>\n<\/tr>\n<tr>\n<td>DL-\u03b1-amino-n-butyrate<\/td>\n<td class=\"center\">\uff0d<\/td>\n<td class=\"center\">\uff0b<\/td>\n<td class=\"center\">\uff0b<\/td>\n<td class=\"center\">\uff0b<\/td>\n<td class=\"center\">\uff0b<\/td>\n<td class=\"center\">\uff0b<\/td>\n<\/tr>\n<tr>\n<td colspan=\"7\"><i>B. mallei<\/i>\u306f\u904b\u52d5\u6027\u30de\u30a4\u30ca\u30b9\u3001 <i>B. pseudomallei<\/i>\u306f\u904b\u52d5\u6027\u30d7\u30e9\u30b9<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<h4>\u907a\u4f1d\u5b50\u3092\u4f7f\u3063\u305f\u691c\u51fa\u3068\u540c\u5b9a<\/h4>\n<p>16S rDNA\u914d\u5217\u3092\u6c7a\u5b9a\u3059\u308b\u304b\u4e0b\u8a18\u306e\u7279\u7570 Primer\u3067 PCR\u6cd5\u3092\u884c\u3046\u306e\u304c\u540c\u5b9a\u3068\u3057\u3066\u306f\u5bb9\u6613\u3067\u3042\u308b\u3002<br \/>\nForward:5&#8242;-TAATACCGCATACGATCTGAGGA-3&#8242;<br \/>\nReverse:5&#8242;-CACTCCGGGTATTAGCCAGAATG-3&#8242;<br \/>\nAnealing\u6e29\u5ea6\uff1a 60C, Amplicon: 308 bp\u3053\u306e primer\u3067\u306f\u3001<i>B. mallei<\/i>\u3068<i>B. pseudomallei<\/i>\u304c\u5897\u5e45\u3057\u3001<i>B. thailandensis<\/i>\u306eDNA\u306f\u5897\u5e45\u3057\u306a\u3044\u3002<\/p>\n<p style=\"text-align: right\"><a title=\"\u9f3b\u75bd\u30fb\u985e\u9f3b\u75bd \u2013 Glanders, Melioidosis\uff08\u8a73\u7d30\uff09\" href=\"\/\/h-crisis.niph.go.jp\/bt\/disease\/7summary\/7detail\/\">\u25b2TOP<\/a><\/p>\n<h3>\u6cbb\u7642<\/h3>\n<h4>\u85ac\u7269\u7642\u6cd5\uff08\u6297\u83cc\u85ac\u7642\u6cd5\uff09<\/h4>\n<h5>\u9f3b\u75bd<\/h5>\n<p>\u305f\u3060\u3057\u9f3b\u75bd\u306f\u60a3\u8005\u306e\u6570\u304c\u5c11\u306a\u304f\u3001\u6297\u83cc\u85ac\u306e\u6709\u52b9\u6027\u306b\u5bfe\u3059\u308b\u81e8\u5e8a\u7684\u306a\u8a55\u4fa1\u306f\u5b9a\u307e\u3063\u3066\u3044\u306a\u3044\u3002\u5206\u96e2\u83cc\u306e\u85ac\u5264\u611f\u53d7\u6027\u306e\u7d50\u679c\u3092\u3082\u3068\u306b\uff0c\u30c6\u30c8\u30e9\u30b5\u30a4\u30af\u30ea\u30f3\u3001ST\u5408\u5264\u304c\u6709\u52b9\u3068\u3055\u308c\u3066\u3044\u308b\u3002\u5fae\u91cf\u6db2\u4f53\u5e0c\u91c8\u6cd5\u3092\u7528\u3044\u305f\u9f3b\u75bd\u83cc\u306eMIC\u6e2c\u5b9a\u306e\u7d50\u679c\u3001\u30bb\u30d5\u30bf\u30b8\u30b8\u30e0\u3001\u30a4\u30df\u30da\u30cd\u30e0\u3001\u30b7\u30d7\u30ed\u30d5\u30ed\u30ad\u30b5\u30b7\u30f3\u3001\u304a\u3088\u3073\u30b2\u30f3\u30bf\u30de\u30a4\u30b7\u30f3\u304c\u826f\u597d\u306a\u52b9\u679c\u3092\u793a\u3057\u3001\u4e2d\u3067\u3082\u30b2\u30f3\u30bf\u30de\u30a4\u30b7\u30f3\u306eMIC90\u306f0.5 \u03bcg\/ml\u3068\u6700\u3082\u6709\u52b9\u3067\u3042\u3063\u305f\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u3002<\/p>\n<p>\u91cd\u75c7\u4f8b\u306b\u304a\u3044\u3066\u306f\u30a2\u30df\u30ce\u30b0\u30ea\u30b3\u30b7\u30c9\u3068ST\u5408\u5264\u306e\u4f75\u7528\u304c\u63a8\u5968\u3055\u308c\u3066\u3044\u308b\u3002\u4e2d\u7b49\u75c7\u4f8b\u3067\u306fST\u5408\u5264\u3042\u308b\u3044\u306f\u30c6\u30c8\u30e9\u30b5\u30a4\u30af\u30ea\u30f3\u3092\u7528\u3044\u308b\u3002\u6cbb\u7642\u306e\u671f\u9593\u306f\uff13\u9031\u9593\u3092\u76ee\u5b89\u3068\u3057\u3066\u3001\u81e8\u5e8a\u7d4c\u904e\u3092\u3082\u3068\u306b\u3055\u3089\u306b\u671f\u9593\u3092\u5ef6\u9577\u3059\u308b\u3002<\/p>\n<h5>\u985e\u9f3b\u75bd<\/h5>\n<p>\u6025\u6027\u611f\u67d3\u306e\u5834\u5408\u3001\u30bb\u30d5\u30bf\u30b8\u30b8\u30e0\u3001\u30a2\u30e2\u30ad\u30b7\u30b7\u30ea\u30f3\/\u30af\u30e9\u30d6\u30e9\u30f3\u9178\u3001\u30e1\u30ed\u30da\u30cd\u30e0\u3001\u3042\u308b\u3044\u306f\u30a4\u30df\u30da\u30cd\u30e0\u306e\u70b9\u6ef4\u9759\u6ce8\u304c\u884c\u308f\u308c\u308b\u3002\u6cbb\u7642\u306f10\uff5e14\u65e5\u9593\u7d99\u7d9a\u3059\u308b\uff0e\u6025\u6027\u671f\u306e\u6cbb\u7642\u306b\u5f15\u304d\u7d9a\u3044\u3066\u3001ST\u5408\u5264\u3001\u30c9\u30ad\u30b7\u30b5\u30a4\u30af\u30ea\u30f3\u306b\u3088\u308b\u4f75\u7528\u7642\u6cd5\u3092\u884c\u3046\u3002<\/p>\n<h4>\u305d\u306e\u4ed6\u6cbb\u7642\u4e0a\u306e\u7559\u610f\u70b9<\/h4>\n<h5>\u9f3b\u75bd<\/h5>\n<p>\u9f3b\u75bd\u306f\u6cbb\u7642\u304c\u9045\u308c\u308b\u3068\u81f4\u547d\u7684\u306a\u72b6\u614b\u306b\u306a\u308b\u5834\u5408\u304c\u3042\u308a\u3001\u65e9\u671f\u306e\u6297\u83cc\u85ac\u6295\u4e0e\u304c\u5fc5\u8981\u3067\u3042\u308b\u3002<\/p>\n<h5>\u985e\u9f3b\u75bd<\/h5>\n<p>\u985e\u9f3b\u75bd\u306e\u518d\u767a\u4e88\u9632\u306f\u3001\u4e0a\u8a18\u306e\u3088\u3046\u306bST\u5408\u5264\u3068\u30c9\u30ad\u30b7\u30b5\u30a4\u30af\u30ea\u30f3\u3092\u4f75\u7528\u3057\u306612\uff5e20\u9031\u9593\u7a0b\u5ea6\u7d99\u7d9a\u3059\u308b\u300220\u9031\u9593\u7a0b\u5ea6\u306e\u4f75\u7528\u7642\u6cd5\u306b\u3088\u308a\uff0c\u985e\u9f3b\u75bd\u306e\u518d\u767a\u306f10%\u4ee5\u4e0b\u306b\u6291\u3048\u3089\u308c\u308b\u3068\u3044\u3046\u5831\u544a\u304c\u3042\u308b\u3002<\/p>\n<p style=\"text-align: right\"><a title=\"\u9f3b\u75bd\u30fb\u985e\u9f3b\u75bd \u2013 Glanders, Melioidosis\uff08\u8a73\u7d30\uff09\" href=\"\/\/h-crisis.niph.go.jp\/bt\/disease\/7summary\/7detail\/\">\u25b2TOP<\/a><\/p>\n<h3>\u4e88\u9632\uff08\u30ef\u30af\u30c1\u30f3\uff09<\/h3>\n<p>\u5229\u7528\u53ef\u80fd\u306a\u30ef\u30af\u30c1\u30f3\u306f\u306a\u3044\u3002<\/p>\n<p style=\"text-align: right\"><a href=\"#toc\">\u25b2TOP<\/a><\/p>\n<h3>\u30d0\u30a4\u30aa\u30cf\u30b6\u30fc\u30c9\u5bfe\u7b56<\/h3>\n<p>\u6587\u732e\u7684\u306b\u306f\u30d2\u30c8\u304b\u3089\u30d2\u30c8\u3078\u306e\u76f4\u63a5\u306e\u611f\u67d3\u306f\u8d77\u3053\u308a\u306b\u304f\u3044\u3068\u3044\u3046\u8a18\u8ff0\u3082\u3042\u308b\u304c\u3001\u5b9f\u969b\u306b\u8d77\u3053\u3063\u305f\u4f8b\u3082\u3042\u308b\u305f\u3081\u60a3\u8005\u306e\u9694\u96e2\u306b\u3064\u3044\u3066\u3082\u8003\u616e\u3059\u308b\u3002\u3055\u3089\u306b\u76ae\u819a\u306b\u75c5\u5de3\u304c\u3042\u308b\u5834\u5408\u306f\u5206\u6ccc\u7269\u4e2d\u306e\u83cc\u306b\u89e6\u308c\u3066\u4ed6\u8005\u306b\u4f1d\u64ad\u3059\u308b\u53ef\u80fd\u6027\u3082\u3042\u308a\u3001\u5580\u75f0\u3084\u5206\u6ccc\u7269\u304c\u4ed8\u7740\u3057\u305f\u7269\u54c1\u306b\u3064\u3044\u3066\u306f\u30aa\u30fc\u30c8\u30af\u30ec\u30fc\u30d6\u306b\u3066\u51e6\u7406\u3092\u3059\u308b\u3002\u672c\u83cc\u306b\u6c5a\u67d3\u3055\u308c\u305f\u7269\u54c1\u306e\u8868\u9762\u306e\u6d88\u6bd2\u306b\u306f0.5\u301c1%\u306e\u6b21\u4e9c\u5869\u7d20\u9178\u30ca\u30c8\u30ea\u30a6\u30e0\u308470% \u30a8\u30bf\u30ce\u30fc\u30eb\u306a\u3069\u304c\u7528\u3044\u3089\u308c\u308b\u3002\u71b1\u306b\u5bfe\u3057\u3066\u306f\u3001\u9f3b\u75bd\u83cc\u306f55\u2103\u300110\u5206\u9593\u306e\u52a0\u71b1\u3067\u6b7b\u6ec5\u3059\u308b\u3002\u306a\u304a\u75c5\u539f\u4f53\u3092\u542b\u3080\u691c\u4f53\u3084\u83cc\u306e\u53d6\u308a\u6271\u3044\u306f\u3001\u5b9f\u9a13\u5ba4\u5185\u3067\u611f\u67d3\u3057\u305f\u4f8b\u3082\u3042\u308b\u306e\u3067\u6ce8\u610f\u304c\u5fc5\u8981\u3067\u3042\u308b\u3002<\/p>\n<div class=\"page\" title=\"Page 1\">\n<div class=\"layoutArea\">\n<div class=\"column\">\n<p>\u308f\u304b\u3099\u56fd\u3066\u3099\u306f\u3001\u5e73\u621019\u5e744\u6708\u304b\u3089\u611f\u67d3\u75c7\u306e\u4e88\u9632\u53ca\u3072\u3099\u611f\u67d3\u75c7\u306e\u60a3\u8005\u306b\u5bfe\u3059\u308b\u533b\u7642\u306b\u95a2\u3059\u308b\u6cd5\u5f8b (\u5e73\u621010\u5e74\u6cd5\u5f8b\u7b2c114\u53f7)\u53ca\u3072\u3099\u611f\u67d3\u75c7\u306e\u4e88\u9632\u53ca\u3072\u3099\u611f\u67d3\u75c7\u306e\u60a3\u8005\u306b\u5bfe\u3059\u308b\u533b\u7642\u306b\u95a2\u3059\u308b\u6cd5\u5f8b\u65bd \u884c\u4ee4(\u5e73\u621010\u5e74\u653f\u4ee4\u7b2c420\u53f7)\u306b\u304a\u3044\u3066\u985e\u9f3b\u75bd\u30924\u985e\u611f\u67d3\u75c7\u306b\u4f4d\u7f6e\u3064\u3099\u3051\u3001\u985e\u9f3b\u75bd\u306e\u60a3\u8005\u3092\u8a3a \u65ad\u3057\u305f\u533b\u5e2b\u306f\u3001\u90fd\u9053\u5e9c\u770c\u77e5\u4e8b\u7b49\u306b\u5bfe\u3057\u3066\u76f4\u3061\u306b\u5c4a\u3051\u51fa\u308b\u3053\u3068\u3092\u7fa9\u52d9\u3064\u3099\u3051\u3066\u3044\u308b\u3002<\/p>\n<p>\u65e5\u672c\u3066\u3099\u306f\u3001\u3053\u308c\u307e\u3066\u3099\u6d77\u5916\u6e21\u822a\u6b74\u306e\u3042\u308b\u60a3\u8005\u306b\u3088\u308b\u8f38\u5165\u611f\u67d3\u75c7\u4f8b\u3068\u3057\u306619\u4f8b\u304b\u3099\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u304c\u3001\u5148\u822c\u3001\u7c73\u56fd\u306b\u304a\u3044\u3066\u5bb6\u5ead\u7528\u6de1\u6c34\u6c34\u69fd\u3092\u4ecb\u3057\u305f\u985e\u9f3b\u75bd\u75c7\u4f8b\u304b\u3099\u5831\u544a\u3055\u308c\u3001\u6ce8\u610f\u559a\u8d77\u304c\u306a\u3055\u308c\u305f\u00a0(\u5225\u6dfb 2)\u3002\u65e5\u672c\u306b\u304a\u3044\u3066\u3082\u6771\u5357\u30a2\u30b7\u3099\u30a2\u304b\u3089\u306e\u89b3\u8cde\u9b5a\u304b\u3099\u591a\u6570\u8f38\u5165\u3055\u308c\u3066\u304a\u308a\u3001\u540c\u69d8\u306b\u8f38\u5165\u3055\u308c\u305f\u6de1 \u6c34\u71b1\u5e2f\u9b5a\u7b49\u3092\u4ecb\u3057\u3066\u985e\u9f3b\u75bd\u75c7\u4f8b\u304b\u3099\u767a\u751f\u3059\u308b\u304a\u305d\u308c\u3082\u3042\u308b\u3002(14)<\/p>\n<p>\u307e\u305f\u3001\u7c73\u56fd\u75be\u75c5\u4e88\u9632\u7ba1\u7406\u30bb\u30f3\u30bf\u30fc(CDC)\u306f\u30012021\u5e743\u6708\u304b\u30897\u6708\u307e\u3066\u3099\u306e\u9593\u306b\u30a2\u30ed\u30de\u30b9\u30d5\u309a\u30ec \u30fc\u306b\u8d77\u56e0\u3059\u308b\u985e\u9f3b\u75bd\u75c7\u4f8b\u304b\u30994\u4f8b\u767a\u751f(2\u540d\u304b\u3099\u6b7b\u4ea1)\u3057\u305f\u3068\u767a\u8868\u3057\u305f(\u5225\u6dfb3)\u3002\u3053\u308c\u307e \u3066\u3099\u306e\u8abf\u67fb\u3066\u3099\u306f\u3001\u5f53\u8a72\u30a2\u30ed\u30de\u30b9\u30d5\u309a\u30ec\u30fc\u306f\u8a66\u9a13\u7684\u306b\u88fd\u9020\u3055\u308c\u305f\u3082\u306e\u3066\u3099\u7c73\u56fd\u5185\u3066\u3099\u306e\u307f\u9650\u5b9a\u7684\u306b\u6d41\u901a \u3057\u3066\u3044\u305f\u3068\u3044\u3046\u3053\u3068\u3060\u304b\u3099\u3001\u672c\u4e8b\u4f8b\u306f\u3053\u3046\u3057\u305f\u88fd\u54c1\u304b\u3099\u985e\u9f3b\u75bd\u306e\u767a\u751f\u8981\u56e0\u306b\u306a\u308a\u5f97\u308b\u3053\u3068\u3092\u793a\u3057 \u3066\u3044\u308b.<\/p>\n<\/div>\n<div class=\"page\" title=\"Page 1\">\n<div class=\"layoutArea\">\n<div class=\"column\">\n<p>\u203b\u75c5\u539f\u4f53\u306e\u691c\u67fb\u7b49\u306b\u95a2\u3059\u308b\u554f\u3044\u5408\u308f\u305b\u5148<\/p>\n<p>\u56fd\u7acb\u611f\u67d3\u75c7\u7814\u7a76\u6240\u6751\u5c71\u5e81\u820e \u7d30\u83cc\u7b2c\u4e8c\u90e8 \u62c5\u5f53:\u5800\u91ce\u6566\u5b50\u3001\u68ee\u8302\u592a\u90ce \u96fb\u8a71\u756a\u53f7:042-561-0771<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<p style=\"text-align: right\"><a title=\"\u9f3b\u75bd\u30fb\u985e\u9f3b\u75bd \u2013 Glanders, Melioidosis\uff08\u8a73\u7d30\uff09\" href=\"\/\/h-crisis.niph.go.jp\/bt\/disease\/7summary\/7detail\/\">\u25b2TOP<\/a><\/p>\n<h3>\u53c2\u8003\u6587\u732e<\/h3>\n<ol>\n<li>Lowe P, Engler C, and Norton R. Comparison of Automated and Nonautomated Systems for Identification of<i>Burkholderia pseudomallei<\/i>. J Clin Microbiol 40:4625-4627, 2002.<\/li>\n<li>Everett ED, and Nelson RA. Pulmonary melioidosis: observations in thirty-nine cases. Am Rev Respir Dis 112:331-340, 1975.<\/li>\n<li>Chaowagul W, Suputtamongkul Y, Smith MD, and White NJ. Oral quinolones for maintenance treatment of melioidosis. Trans R Soc Trop Med Hyg 91:599-601, 1997.<\/li>\n<li>Lew AE, Desmarchelier PM. D<i>etec<\/i>tion of Pseudomonas pseudomallei by PCR and hybridization. J Clin Microbiol 32:1326-1332, 1994.<\/li>\n<li>Naigowit P, Kurata T, et al. Application of indirect immunofluorescence microscopy to colony identification of Pseudomonas pseudomallei, Asian Pac J Allergy Immunol 11:149-154, 1993.<\/li>\n<li>Smith MD, Wuthiekanun V, et al. Latex agglutination test for identification of Pseudomonas pseudomallei, J Clin Pathol 46: 374-375, 1993.<\/li>\n<li>Rajchanuvong A, Chaowagul W, et al. A prospective comparison of co-amoxiclav and the combination of chloramphenicol, doxycycline, and co-trimoxazole for the oral maintenancetreatment of melioidosis, Trans R Soc Trop Med Hyg 89: 546-549, 1995.<\/li>\n<li>Kenny DJ, Russell P, Rogers D, Eley SM, Titball RW. In vitro susceptibilities of <i>Burkholderia mallei<\/i> in comparison to those of other pathogenic <i>Burkholderia<\/i> spp. Antimicrob Agents Chemother 43:2773-2775, 1999.<\/li>\n<li>Deitchman S, Sokas R. Glanders in a military research microbiologist.N Engl J Med 345:1644, 2001.<\/li>\n<li>Kenny DJ, Russell P, Rogers D, Eley SM, Titball RW. In vitro susceptibilities of <i>Burkholderia mallei<\/i> in comparison to those of other pathogenic <i>Burkholderia<\/i> spp. Antimicrob Agents Chemother 43:2773-2775, 1999<\/li>\n<li>Harrison&#8217;s Principles of Internal Medicine, 16th ed. Braunwald, E.et al. Ed. McGraw-Hill, 2004<\/li>\n<li>Gilbert,DN, et al. Sanford Guide to Antimicrobial Therapy, 2005<\/li>\n<li>Laboratory Exposure to <i>Burkholderia pseudomallei<\/i> &#8211; Los Angeles, California, MMWR 53:988\uff0d990, 2003<\/li>\n<li>\u539a\u751f\u52b4\u50cd\u7701\u5065\u5eb7\u5c40\u7d50\u6838\u611f\u67d3\u75c7\u8ab2\u3000\u901a\u77e5 2021.12.27<\/li>\n<\/ol>\n<p style=\"text-align: right\"><a title=\"\u9f3b\u75bd\u30fb\u985e\u9f3b\u75bd \u2013 Glanders, Melioidosis\uff08\u8a73\u7d30\uff09\" href=\"\/\/h-crisis.niph.go.jp\/bt\/disease\/7summary\/7detail\/\">\u25b2TOP<\/a><\/p>\n<div class=\"timestamp\" style=\"text-align: right\">2009\u5e7411\u670809\u65e5 18\u664245\u5206 \u6539\u8a02<\/div>\n","protected":false},"excerpt":{"rendered":"<p>\u75c5\u539f\u4f53\u306e\u7279\u5fb4 \u9f3b\u75bd\u83cc\u3001\u985e\u9f3b\u75bd\u83cc\u3001\u3044\u305a\u308c\u3082\u751f\u7269\u5175\u5668\u3078\u306e\u5fdc\u7528\u3092\u76ee\u7684\u306b\u7814\u7a76\u304c\u884c\u308f\u308c\u305f\u904e\u53bb\u304c\u3042\u308a\u3001\u7c73\u56fd\uff23\uff24\uff23\u306f\u30d0\u30a4\u30aa\u30c6\u30ed\u76ee\u7684\u3067\u4f7f\u7528\u3055\u308c\u308b\u53ef\u80fd\u6027\u304c\u9ad8\u3044\u83cc\u3068\u3057\u3066\u3001\u3053\u306e2\u3064\u306e\u83cc\u3092\u30ab\u30c6\u30b4\u30ea\u30fc\uff22\u306b\u5206\u985e\u3057\u3066\u3044\u308b\u3002 \u9f3b\u75bd\u83cc\u3001\u985e\u9f3b\u75bd\u83cc\u3068\u3082\u306b\u6771\u5357\u2026 <span class=\"read-more\"><a href=\"https:\/\/h-crisis.niph.go.jp\/bt\/disease\/7summary\/7detail\/\">\u7d9a\u304d\u3092\u8aad\u3080 &raquo;<\/a><\/span><\/p>\n","protected":false},"author":12,"featured_media":0,"parent":118,"menu_order":2,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/h-crisis.niph.go.jp\/bt\/wp-json\/wp\/v2\/pages\/282"}],"collection":[{"href":"https:\/\/h-crisis.niph.go.jp\/bt\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/h-crisis.niph.go.jp\/bt\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/h-crisis.niph.go.jp\/bt\/wp-json\/wp\/v2\/users\/12"}],"replies":[{"embeddable":true,"href":"https:\/\/h-crisis.niph.go.jp\/bt\/wp-json\/wp\/v2\/comments?post=282"}],"version-history":[{"count":15,"href":"https:\/\/h-crisis.niph.go.jp\/bt\/wp-json\/wp\/v2\/pages\/282\/revisions"}],"predecessor-version":[{"id":1468,"href":"https:\/\/h-crisis.niph.go.jp\/bt\/wp-json\/wp\/v2\/pages\/282\/revisions\/1468"}],"up":[{"embeddable":true,"href":"https:\/\/h-crisis.niph.go.jp\/bt\/wp-json\/wp\/v2\/pages\/118"}],"wp:attachment":[{"href":"https:\/\/h-crisis.niph.go.jp\/bt\/wp-json\/wp\/v2\/media?parent=282"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}