{"id":1129,"date":"2018-03-19T04:38:31","date_gmt":"2018-03-19T04:38:31","guid":{"rendered":"https:\/\/niph.log.mixh.jp\/?page_id=1129"},"modified":"2022-10-19T14:04:10","modified_gmt":"2022-10-19T05:04:10","slug":"shimura","status":"publish","type":"page","link":"https:\/\/www.niph.go.jp\/soshiki\/09seikatsu\/shimura\/","title":{"rendered":"\u751f\u6d3b\u74b0\u5883\u7814\u7a76\u90e8-\u5fd7\u6751\u52c9"},"content":{"rendered":"<style>\r\ntd:first-child {white-space:nowrap;}\r\n@media screen and ( max-width: 677px ) {\r\ntd {\r\n    width: 100%;\r\n    display: block;\r\npadding: 0.4em 0;\r\n\t}\r\n.rwspn5 {display:none;}\r\ntable {margin-left: 1% !important;}\r\n\t}\r\n\r\n<\/style>\r\n\r\n<div class=\"container-fluid\" style=\"margin:0;padding:0;\">\r\n<div class=\"row\" style=\"margin:0;padding:0;\">\r\n<!----[myphp file='menu']---->\r\n<div class=\"\" style=\"padding:0;\">\r\n<div id=\"main\">\r\n\r\n\r\n<div id=\"article\">\r\n<div id=\"pankuzu\"><a href=\"\/\">\u56fd\u7acb\u4fdd\u5065\u533b\u7642\u79d1\u5b66\u9662HOME\u3078<\/a>&nbsp;&gt;&nbsp;<a href=\"\/soshiki\/soshikizu\/\">\u7d44\u7e54<\/a>&nbsp;&gt;&nbsp;<a href=\"\/soshiki\/09seikatsu\/\">\u751f\u6d3b\u74b0\u5883\u7814\u7a76\u90e8<\/a>&nbsp;&gt;&nbsp;<a href=\"\/soshiki\/09seikatsu\/shimura_info\/\">\u5fd7\u6751\u52c9<\/a>&nbsp;&gt;&nbsp;<em>\u7814\u7a76\u5b9f\u7e3e<\/em><\/div>\r\n\r\n<h3>\u751f\u6d3b\u74b0\u5883\u7814\u7a76\u90e8<\/h3>\r\n<div id=\"sName\" class=\"sTitle-name\">\r\n<span>\u4e0a\u5e2d\u4e3b\u4efb\u7814\u7a76\u5b98<br>\r\n<\/span>\r\n<em>\u5fd7\u6751\u3000\u52c9<\/em>\r\n<span class=\"enName\">SHIMURA Tsutomu<\/span>\r\n<!--International cooperation research part--><\/div>\r\n<div id=\"article-in\" class=\"kenkyubu\">\r\n        <!--Main Area Start-->\r\n        <h4>\u5c02\u9580\u5206\u91ce<\/h4>\r\n        <p>\u653e\u5c04\u7dda\u885b\u751f\u5b66<\/p>\r\n        <h4>\u4eba\u6750\u80b2\u6210<\/h4>\r\n        <p>\u77ed\u671f\u7814\u4fee<br>\r\n        \u30fb<a href=\"\/entrance\/r4\/course\/short\/short_kankyo08.html\" target=\"_blank\">\u533b\u7642\u653e\u5c04\u7dda\u306e\u9069\u6b63\u7ba1\u7406\u306b\u95a2\u3059\u308b\u7814\u4fee<\/a>\u3000\u526f\u4e3b\u4efb<br>\r\n        \u30fb<a href=\"\/entrance\/r4\/course\/short\/short_shokuhin04.html\" target=\"_blank\">\u98df\u54c1\u885b\u751f\u76e3\u8996\u6307\u5c0e\u7814\u4fee<\/a>\u3000\u526f\u4e3b\u4efb\r\n        <\/p>\r\n        <!--\u7814\u7a76\u5b9f\u7e3e Start-->\r\n        <h4>\u7814\u7a76\u5b9f\u7e3e<\/h4>\r\n<h5>\u539f\u8457\u8ad6\u6587<\/h5>\r\n<p style=\"padding-left:1em;text-indent:-1em;\">\u30fbShimura T, Nakashiro C, Fujiwara K, Shiga R, Sasatani M, Kamiya K, Ushiyama A.  Radiation affects glutathione redox reaction by reduced glutathione peroxidase activity in human fibroblasts. Journal of Radiation Research 2022;63(2):183-191<\/p>\r\n<p style=\"padding-left:1em;text-indent:-1em;\">\u30fbShimura T, Ando T, Narao M, Sasatani M, Kamiya K, Ushiyama A. Mechanism of turnover or persistence of radiation-induced myofibroblast in vitro. 2020; Cell Cycle.19 (23), 3375-3385<\/p>\r\n<p style=\"padding-left:1em;text-indent:-1em;\">\u30fbShimura T, Nakashiro C, Narao M, Ushiyama A. Induction of oxidative stress biomarkers following whole-body irradiation in mice. PLoS One. 2020; 15(10):e0240108. doi: 10.1371\/journal.pone.0240108.<\/p>\r\n<p style=\"padding-left:1em;text-indent:-1em;\">\u30fbShimura T, Koyama M, Aono D, Kunugita N. Epicatechin as a promising agent to countermeasure radiation exposure by mitigating mitochondrial damage in human fibroblasts and mouse hematopoietic cells. The FASEB J 2019; 33 (6), 6867-6876<\/p>\r\n\r\n<h5>\u7dcf\u8aac<\/h5>\r\n<p style=\"padding-left:1em;text-indent:-1em;\">\u30fbShimura T. ATM-Mediated Mitochondrial Radiation Responses of Human Fibroblasts. Genes 2021; 12(7).<\/p>\r\n<p style=\"padding-left:1em;text-indent:-1em;\">\u30fbShimura T. The role of mitochondrial oxidative stress and the tumor microenvironment in radiation-related cancer. Journal of radiation research 2021; 62(Supplement_1) i36-i43.<\/p>\r\n<p style=\"padding-left:1em;text-indent:-1em;\">\u30fbShimura T. Roles of Fibroblasts in Microenvironment Formation Associated with Radiation-Induced Cancer. Advances in experimental medicine and biology Tumor microenvironment: Novel Concepts 2021; 1329 239-251.<\/p>\r\n<p style=\"padding-left:1em;text-indent:-1em;\">\u30fb\u5fd7\u6751\u52c9\uff0c\u5c71\u53e3\u4e00\u90ce\uff0c\u5bfa\u7530\u5b99\uff0c\u6e29\u6cc9\u5ddd\u8087\u5f66\uff0c\u725b\u5c71\u660e \u30c8\u30ea\u30c1\u30a6\u30e0\u306e\u751f\u4f53\u3078\u306e\u5f71\u97ff\u3068\u4f4e\u7dda\u91cf\u653e\u5c04\u7dda\u5f71\u97ff\u7814\u7a76\u306e\u8ab2\u984c \u4fdd\u5065\u533b\u7642\u79d1\u5b66\u30002021;.70 (.2), 160\uff0d165<\/p>\r\n\r\n<h5>\u5b66\u4f1a\u767a\u8868<\/h5>\r\n<p style=\"padding-left:1em;text-indent:-1em;\">\u30fbShimura T, Ushiyama A Mitochondrial damage as a biological marker for dose assessment. EPR BioDose 2022; 2022; Okayama, Japan; 2022. p. 22<\/p>\r\n<p style=\"padding-left:1em;text-indent:-1em;\">\u30fbShimura T, Nakashiro C,Fujiwara K, Shiga R, Ushiyama A \u3000Radiation-induced inactivation of glutathione peroxidase activity in human fibroblasts for disruption of glutathione redox homeostasis\u3000\u65e5\u672c\u653e\u5c04\u7dda\u5f71\u97ff\u5b66\u4f1a\u7b2c64\u56de; 2021, p. 100<\/p>\r\n\r\n<h4>\u793e\u4f1a\u8ca2\u732e<\/h4>\r\n<p>\u516c\u76ca\u8ca1\u56e3\u6cd5\u4eba\u74b0\u5883\u79d1\u5b66\u6280\u8853\u7814\u7a76\u6240\u3000\u4f4e\u7dda\u91cf\u7387\u653e\u5c04\u7dda\u306b\u5bfe\u3059\u308b\u751f\u7406\u5fdc\u7b54\u5f71\u97ff\u5b9f\u9a13\u8abf\u67fb\uff08\u7b2c2\u671f\uff09\u59d4\u54e1<\/p>\r\n<p>\u65e5\u672c\u653e\u5c04\u7dda\u5f71\u97ff\u5b66\u4f1a\u3000\u5b66\u4f1a\u8a8c\u3000Journal of Radiation Research\u306e\u7de8\u96c6\u59d4\u54e1<\/p>\r\n<p>\u516c\u76ca\u8ca1\u56e3\u6cd5\u4eba\u3000\u539f\u5b50\u529b\u5b89\u5168\u7814\u7a76\u5354\u4f1a\u3000\u751f\u7269\u5f71\u97ff\u691c\u8a0e\u4f1a\u59d4\u54e1<\/p>\r\n\r\n<h4>\u305d\u306e\u4ed6\uff08\u53d7\u8cde\u6b74\u7b49\uff09<\/h4>\r\n<p>2015 ICRR2015 Excellent Poster Award\uff08\u7b2c15\u56de\u56fd\u969b\u653e\u5c04\u7dda\u7814\u7a76\u4f1a\u8b70 ICRR2015\u512a\u79c0\u30dd\u30b9\u30bf\u30fc\u767a\u8868\u8cde\uff09<\/p>\r\n\r\n\r\n        <!--\u7814\u7a76\u5b9f\u7e3e End--> \r\n        \r\n        <!--Main Area End-->\r\n      <\/div>\r\n<\/div>\r\n\r\n\r\n<\/div><!--main end-->\r\n<\/div><!--col end-->\r\n<\/div><!--row end-->\r\n<\/div><!------- container-fluid end -------->","protected":false},"excerpt":{"rendered":"\u56fd\u7acb\u4fdd\u5065\u533b\u7642\u79d1\u5b66\u9662HOME\u3078&nbsp;&gt;&nbsp;\u7d44\u7e54&nbsp;&gt;&nbsp;\u751f\u6d3b\u74b0\u5883\u7814\u7a76\u90e8&nbsp;&gt;&nbsp;\u5fd7\u6751\u52c9&nbsp;&gt;&nbsp;\u7814\u7a76\u5b9f\u7e3e \u751f\u6d3b\u74b0\u5883\u7814\u7a76\u90e8 \u4e0a\u5e2d\u4e3b\u4efb\u7814\u7a76\u5b98 &hellip; <p class=\"link-more\"><a href=\"https:\/\/www.niph.go.jp\/soshiki\/09seikatsu\/shimura\/\" class=\"more-link\"><span class=\"screen-reader-text\">&#8220;\u751f\u6d3b\u74b0\u5883\u7814\u7a76\u90e8-\u5fd7\u6751\u52c9&#8221; \u306e<\/span>\u7d9a\u304d\u3092\u8aad\u3080<\/a><\/p>","protected":false},"author":1,"featured_media":0,"parent":711,"menu_order":70,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/www.niph.go.jp\/wp-json\/wp\/v2\/pages\/1129"}],"collection":[{"href":"https:\/\/www.niph.go.jp\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.niph.go.jp\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.niph.go.jp\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.niph.go.jp\/wp-json\/wp\/v2\/comments?post=1129"}],"version-history":[{"count":12,"href":"https:\/\/www.niph.go.jp\/wp-json\/wp\/v2\/pages\/1129\/revisions"}],"predecessor-version":[{"id":8927,"href":"https:\/\/www.niph.go.jp\/wp-json\/wp\/v2\/pages\/1129\/revisions\/8927"}],"up":[{"embeddable":true,"href":"https:\/\/www.niph.go.jp\/wp-json\/wp\/v2\/pages\/711"}],"wp:attachment":[{"href":"https:\/\/www.niph.go.jp\/wp-json\/wp\/v2\/media?parent=1129"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}