Department of Environmental Health

 

Department Director
USHIYAMA Akira

Specialty

Environmental Health, Hygiene, Environment Physiology

Works

Original papers

1 Nishida R, Suzuki D, Akimoto Y, Matsubara S, Hayakawa J, Ushiyama A, Sasa K, Miyamoto Y, Iijima T, Kamijo R. Exploring the pathophysiological mechanism of interstitial edema focusing on the role of macrophages and their interaction with the glycocalyx. J Oral Biosci. 2023 Mar;65(1):111-118. doi: 10.1016/j.job.2023.01.001. Epub 2023 Jan 11. PMID: 36640838.

2 Ohtani S, Ushiyama A, Wada K, Suzuki Y, Hattori K. In vivo genotoxicity of high-intensity intermediate frequency magnetic fields in somatic cells and germ cells. J Radiat Res. 2023 Mar 23;64(2):250-260. doi: 10.1093/jrr/rrac081. PMID: 36579461; PMCID: PMC10036096.

3 Ando T, Uzawa K, Yoshikawa T, Mitsuda S, Akimoto Y, Yorozu T, Ushiyama A. The effect of tetrastarch on the endothelial glycocalyx layer in early hemorrhagic shock using fluorescence intravital microscopy: a mouse model. J Anesth. 2023 Feb;37(1):104-118. doi: 10.1007/s00540-022-03138-4. Epub 2022 Nov 24. PMID: 36427094; PMCID: PMC9870981.

4 Sawa M, Ushiyama A, Inaba Y, Hattori K. Increased oxidative stress and effects on inflammatory cytokine secretion by heated tobacco products aerosol exposure to mice. Biochem Biophys Res Commun. 2022 Jun 25;610:43-48. doi: 10.1016/j.bbrc.2022.04.042. Epub 2022 Apr 11. PMID: 35462100.

5 Shinohara A, Ushiyama A, Iijima T. Time-Dependent Dynamics Required for the Degradation and Restoration of the Vascular Endothelial Glycocalyx Layer in Lipopolysaccharide-Treated Septic Mice. Front Cardiovasc Med. 2021 Sep 14;8:730298. doi: 10.3389/fcvm.2021.730298. PMID: 34595224; PMCID: PMC8476805.

6 Wakatsuki M, Takaki T, Ushiyama A, Honda K, Iijima T. Fast-track preparation of lung specimens for electron microscope observations of the pulmonary endothelial glycocalyx. Med Mol Morphol. 2023 Jul 5. doi: 10.1007/s00795-023-00360-1. Epub ahead of print. PMID: 37405470.

7 Koike S, Sato K, Sawa M, Inaba Y, Hattori K, Nakadate K, Ushiyama A, Ogasawara Y. Exposure to Heated Tobacco Products Aerosol Causes Acute Stress Responses in the Lung of Mouse. Antioxidants (Basel). 2022 Nov 25;11(12):2329. doi: 10.3390/antiox11122329. PMID: 36552537; PMCID: PMC9774187.

8 Mitsuda S, Uzawa K, Sawa M, Ando T, Yoshikawa T, Miyao H, Yorozu T, Ushiyama A. Vascular Endothelial Glycocalyx Plays a Role in the Obesity Paradox According to Intravital Observation. Front Cardiovasc Med. 2021 Nov 2;8:727888. doi: 10.3389/fcvm.2021.727888. PMID: 34796208; PMCID: PMC8593246.

9 Sawa M, Ushiyama A, Inaba Y, Uchiyama S, Hattori K, Ogasawara Y, Ishii K. A Newly Developed Aerosol Exposure Apparatus for Heated Tobacco Products for In Vivo Experiments Can Deliver Both Particles and Gas Phase With High Recovery and Depicts the Time-Dependent Variation in Nicotine Metabolites in Mouse Urine. Nicotine Tob Res. 2021 Nov 5;23(12):2145-2152. doi: 10.1093/ntr/ntab123. PMID: 34111284.

10 Ohtani S, Ushiyama A, Wada K, Suzuki Y, Ishii K, Hattori K. No evidence for genotoxicity in mice due to exposure to intermediate-frequency magnetic fields used for wireless power-transfer systems. Mutat Res Genet Toxicol Environ Mutagen. 2021 Mar-Apr;863-864:503310. doi: 10.1016/j.mrgentox.2021.503310. Epub 2021 Jan 19. PMID: 33678242.

11 Uzawa K, Ushiyama A, Mitsuda S, Ando T, Sawa M, Miyao H, Yorozu T. The protective effect of hydroxyethyl starch solution on the glycocalyx layer in an acute hemorrhage mouse model. J Anesth. 2020 Feb;34(1):36-46. doi: 10.1007/s00540-019-02692-8. Epub 2019 Oct 15. PMID: 31617003; PMCID: PMC6992552.

12 Ohtani S, Ushiyama A, Maeda M, Wada K, Suzuki Y, Hattori K, Kunugita N, Ishii K. Global Analysis of Transcriptional Expression in Mice Exposed to Intermediate Frequency Magnetic Fields Utilized for Wireless Power Transfer Systems. Int J Environ Res Public Health. 2019 May 25;16(10):1851. doi: 10.3390/ijerph16101851. PMID: 31130593; PMCID: PMC6572459.

Others (awards, etc.)

Associate Editor of “Journal of Radiation Research”

Associate Editor of “Bioelectromagnetics”

A member of “the Expert Group on Article 9 and 10 of the WHO FCTC”

A member of “International advisory committee of WHO international EMF project”