専門分野

生活環境学、衛生学、環境生理学

人材育成

専門課程
1 保健福祉行政管理分野分割前期（基礎）　必修科目「環境保健概論」担当者

短期研修
1 DHEAT標準編研修　副主任
2 たばこ対策の施策推進における企画・調整のための研修　副主任

研究実績

原著論文

1 Nishida R, Suzuki D, Akimoto Y, Matsubara S, Hayakawa J, Ushiyama A, Sasa K, Miyamoto Y, Iijima T, Kamijo R. Exploring the pathophysiological mechanism of interstitial edema focusing on the role of macrophages and their interaction with the glycocalyx. J Oral Biosci. 2023 Mar;65(1):111-118. doi: 10.1016/j.job.2023.01.001. Epub 2023 Jan 11. PMID: 36640838.

2 Ohtani S, Ushiyama A, Wada K, Suzuki Y, Hattori K. In vivo genotoxicity of high-intensity intermediate frequency magnetic fields in somatic cells and germ cells. J Radiat Res. 2023 Mar 23;64(2):250-260. doi: 10.1093/jrr/rrac081. PMID: 36579461; PMCID: PMC10036096.

3 Ando T, Uzawa K, Yoshikawa T, Mitsuda S, Akimoto Y, Yorozu T, Ushiyama A. The effect of tetrastarch on the endothelial glycocalyx layer in early hemorrhagic shock using fluorescence intravital microscopy: a mouse model. J Anesth. 2023 Feb;37(1):104-118. doi: 10.1007/s00540-022-03138-4. Epub 2022 Nov 24. PMID: 36427094; PMCID: PMC9870981.

4 Sawa M, Ushiyama A, Inaba Y, Hattori K. Increased oxidative stress and effects on inflammatory cytokine secretion by heated tobacco products aerosol exposure to mice. Biochem Biophys Res Commun. 2022 Jun 25;610:43-48. doi: 10.1016/j.bbrc.2022.04.042. Epub 2022 Apr 11. PMID: 35462100.

5 Shinohara A, Ushiyama A, Iijima T. Time-Dependent Dynamics Required for the Degradation and Restoration of the Vascular Endothelial Glycocalyx Layer in Lipopolysaccharide-Treated Septic Mice. Front Cardiovasc Med. 2021 Sep 14;8:730298. doi: 10.3389/fcvm.2021.730298. PMID: 34595224; PMCID: PMC8476805.

6 Wakatsuki M, Takaki T, Ushiyama A, Honda K, Iijima T. Fast-track preparation of lung specimens for electron microscope observations of the pulmonary endothelial glycocalyx. Med Mol Morphol. 2023 Jul 5. doi: 10.1007/s00795-023-00360-1. Epub ahead of print. PMID: 37405470.

7 Koike S, Sato K, Sawa M, Inaba Y, Hattori K, Nakadate K, Ushiyama A, Ogasawara Y. Exposure to Heated Tobacco Products Aerosol Causes Acute Stress Responses in the Lung of Mouse. Antioxidants (Basel). 2022 Nov 25;11(12):2329. doi: 10.3390/antiox11122329. PMID: 36552537; PMCID: PMC9774187.

8 Mitsuda S, Uzawa K, Sawa M, Ando T, Yoshikawa T, Miyao H, Yorozu T, Ushiyama A. Vascular Endothelial Glycocalyx Plays a Role in the Obesity Paradox According to Intravital Observation. Front Cardiovasc Med. 2021 Nov 2;8:727888. doi: 10.3389/fcvm.2021.727888. PMID: 34796208; PMCID: PMC8593246.

9 Sawa M, Ushiyama A, Inaba Y, Uchiyama S, Hattori K, Ogasawara Y, Ishii K. A Newly Developed Aerosol Exposure Apparatus for Heated Tobacco Products for In Vivo Experiments Can Deliver Both Particles and Gas Phase With High Recovery and Depicts the Time-Dependent Variation in Nicotine Metabolites in Mouse Urine. Nicotine Tob Res. 2021 Nov 5;23(12):2145-2152. doi: 10.1093/ntr/ntab123. PMID: 34111284.

10 Uzawa K, Ushiyama A, Mitsuda S, Ando T, Sawa M, Miyao H, Yorozu T. The protective effect of hydroxyethyl starch solution on the glycocalyx layer in an acute hemorrhage mouse model. J Anesth. 2020 Feb;34(1):36-46. doi: 10.1007/s00540-019-02692-8. Epub 2019 Oct 15. PMID: 31617003; PMCID: PMC6992552.

11 Ohtani S, Ushiyama A, Maeda M, Wada K, Suzuki Y, Hattori K, Kunugita N, Ishii K. Global Analysis of Transcriptional Expression in Mice Exposed to Intermediate Frequency Magnetic Fields Utilized for Wireless Power Transfer Systems. Int J Environ Res Public Health. 2019 May 25;16(10):1851. doi: 10.3390/ijerph16101851. PMID: 31130593; PMCID: PMC6572459.

社会貢献

日本放射線影響学会　学会誌　Journal of Radiation ResearchのAssociate Editor

国際生体電磁気学会(BioEM)の学会誌、BioelectromagneticsのAssociate Editor

WHOたばこ規制枠組み条約９条１０条に関するエキスパート（専門家）

WHO国際電磁界プロジェクト国際諮問委員会

厚生労働省　厚生科学審議会地域保健健康増進栄養部会たばこの健康影響評価専門委員会委員