生活環境研究部
志村 勉 SHIMURA Tsutomu
専門分野
放射線衛生学
人材育成
短期研修
・医療放射線の適正管理に関する研修 副主任
・食品衛生監視指導研修 副主任
研究実績
原著論文
・Shimura T, Nakashiro C, Fujiwara K, Shiga R, Sasatani M, Kamiya K, Ushiyama A. Radiation affects glutathione redox reaction by reduced glutathione peroxidase activity in human fibroblasts. Journal of Radiation Research 2022;63(2):183-191
・Shimura T, Ando T, Narao M, Sasatani M, Kamiya K, Ushiyama A. Mechanism of turnover or persistence of radiation-induced myofibroblast in vitro. 2020; Cell Cycle.19 (23), 3375-3385
・Shimura T, Nakashiro C, Narao M, Ushiyama A. Induction of oxidative stress biomarkers following whole-body irradiation in mice. PLoS One. 2020; 15(10):e0240108. doi: 10.1371/journal.pone.0240108.
・Shimura T, Koyama M, Aono D, Kunugita N. Epicatechin as a promising agent to countermeasure radiation exposure by mitigating mitochondrial damage in human fibroblasts and mouse hematopoietic cells. The FASEB J 2019; 33 (6), 6867-6876
総説
・Shimura T. ATM-Mediated Mitochondrial Radiation Responses of Human Fibroblasts. Genes 2021; 12(7).
・Shimura T. The role of mitochondrial oxidative stress and the tumor microenvironment in radiation-related cancer. Journal of radiation research 2021; 62(Supplement_1) i36-i43.
・Shimura T. Roles of Fibroblasts in Microenvironment Formation Associated with Radiation-Induced Cancer. Advances in experimental medicine and biology Tumor microenvironment: Novel Concepts 2021; 1329 239-251.
・志村勉,山口一郎,寺田宙,温泉川肇彦,牛山明 トリチウムの生体への影響と低線量放射線影響研究の課題 保健医療科学 2021;.70 (.2), 160-165
学会発表
・Shimura T, Ushiyama A Mitochondrial damage as a biological marker for dose assessment. EPR BioDose 2022; 2022; Okayama, Japan; 2022. p. 22
・Shimura T, Nakashiro C,Fujiwara K, Shiga R, Ushiyama A Radiation-induced inactivation of glutathione peroxidase activity in human fibroblasts for disruption of glutathione redox homeostasis 日本放射線影響学会第64回; 2021, p. 100
社会貢献
公益財団法人環境科学技術研究所 低線量率放射線に対する生理応答影響実験調査(第2期)委員
日本放射線影響学会 学会誌 Journal of Radiation Researchの編集委員
公益財団法人 原子力安全研究協会 生物影響検討会委員
その他(受賞歴等)
2015 ICRR2015 Excellent Poster Award(第15回国際放射線研究会議 ICRR2015優秀ポスター発表賞)